- Forces are moving primarily in an approximating direction
- Compression stimulates bone, cartilage, discogenic tissue, and often neurological tissue.
- When these tissues are overloaded, this leads to fractures, in some cases disc damage, or even nerve compression.
- Examples: stress fracture of vertebrae, disc herniation, cervical radiculopathy, and compartment syndrome. Insufficient loading may lead to osteoporosis for example.