Personal Protective Equipment (PPE)

Original Editor - Rania Nasr Top Contributors - Rania Nasr and Kim Jackson


Infection prevention and control measures include: personal protective equipment, hand hygiene and waste management materials. 

The Protective equipment consists of garments placed to protect the healthcare workers or any other persons from infections. 

The standard precautions consist of: mask, gloves, gown. If it is blood or airborne high infections, it includes: face shield, mask or protection, goggles, gloves, gown or coverall, head cover, rubber boots.

Hierarchy of Safety and Health Controls

According to the Occupational Safety and Health Administration (OSHA) the protection of healthcare workers from infectious disease exposures in the workplace requires a combination of controls:

  1. Training and administrative controls; by providing appropriate safety and infection control training to healthcare professionals, and administrative controls such as establishing and applying isolation policies and procedures, also procedures to identify patients with communicable diseases before the exposure to healthcare worker.
  2. Engineering controls; such as negative pressure rooms for patients with airborne diseases such as TB,
  3. Work practice control; like not recapping needles,
  4. Personal Protective Equipment (PP); although PPE is at the end of the hierarchy of prevention, it is very important for protecting healthcare workers from disease transmission.

Types of PPE

  1. Gloves; protects your hands from germs and helps reduce the spread of germs.
  2. Masks; cover your mouth and nose. Some masks have a see-through plastic part that covers your eyes. A surgical mask helps stop germs in your nose and mouth from spreading. It can also keep you from inhaling some germs. A special respiratory mask (respirator) forms a tight seal around your nose and mouth. It may be needed so that you do not inhale small germs like tuberculosis bacteria.
  3. Eye protection includes face shields and goggles. These protect the mucous membranes in your eyes from blood and other bodily fluids. If these fluids make contact with the eyes, germs in the fluid can enter the body through the mucous membranes.
  4. Clothing includes gowns, aprons, head covering, and shoe covers.

Selection of Appropriate PPE

It is important to consider the following factors influencing the selection of PPE:

  1. Type of anticipated exposure, such as touch, splashes or sprays, or large volumes of blood or body fluids that might penetrate the clothing. PPE selection, in particular the combination of PPE, also is determined by the category of isolation precautions a patient is on.
  2. durability and appropriateness of the PPE for the task. This will affect, for example, whether a gown or apron is selected for PPE, or, if a gown is selected, whether it needs to be fluid resistant, fluid proof, or neither.
  3. Fitting, PPE must fit the individual user. For example; if a glove was bigger than the individual’s size, it might compromise the dexterity, and if it was a smaller size it might get torn during the contact with patients.

There are some limiting factors for wearing PPE in healthcare environment. It is important to have full understanding of selection of appropriate PPE depending on the purpose and goals. Using a head or full body ventilated PPE suits equipped with powered-air-purifying-respirators was found to cause reduced dexterity due to multiple glove layers, back pain related to the respirator of the fully ventilated suit and impaired visibility by flexible face shields. However, there was no negative impact on speed and error rate. Temperature at workplace also has an impact on healthcare workers, as working at a temperature of 28°C wearing a full body ventilated PPE might cause  heat stress and liquid loss. Whereas a temperature of 22°C had no negative impact on the same  physical parameters[1].


Gloves are the most common type of PPE used in healthcare settings. There are different types of glove material, like vinyl, latex, nitrile, it can also be sterile or non-sterile, single use or reusable. Most patient care activities require the use of a single pair of nonsterile gloves made of either latex, nitrile, or vinyl. However, because of allergy concerns, some facilities have eliminated or limited latex products, including gloves, and now use gloves made of nitrile or other material.

Do’s and Don’ts of glove use

The way you use gloves influences the risk of infections and disease transmission in healthcare sittings. These are the most important do’s and don’ts of glove use:

  1. Work from clean to dirty: In this instance it refers to touching clean body sites or surfaces before you touch dirty or heavily contaminated areas.
  2. Limit opportunities for “touch contamination” - protect yourself, others and environmental surfaces. Example of touch contamination, adjusting glasses, rubbing nose or scratching face with glove that has been in contact with a patient. Furthermore, avoid unnecessarily touching environmental surfaces with contaminated gloves. Surfaces such as light switches, door and cabinet knobs can become contaminated if touched by soiled gloves.
  3. Change gloves as needed. Always change gloves after use on each patient, and discard them in the nearest appropriate receptacle.

Gowns or Aprons?

There are 3 factors influencing the selection of a gown or apron:

  1. The purpose of use:  Isolation gowns are generally the preferred PPE for clothing but aprons occasionally are used where limited contamination is anticipated. If contamination of the arms can be anticipated, a gown should be selected. Gowns should fully cover the torso, fit comfortably over the body, and have long sleeves that fit snuggly at the wrist.
  2. The material properties of the gown: Isolation gowns are made either of cotton or a spun synthetic material that dictate whether they can be laundered and reused or must be disposed. Cotton and spun synthetic isolation gowns vary in their degree of fluid resistance, another factor that must be considered in the selection of this garb. If fluid penetration is likely, a fluid resistant gown should be used.
  3. Patient risks and whether a clean, rather than sterile gown, can be used. Clean gowns are generally used for isolation. Sterile gowns are only necessary for performing invasive procedures, such as inserting a central line. In this case, a sterile gown would serve purposes of patient and healthcare worker protection.

Face Protection

Masks should fully cover the nose and mouth and prevent fluid penetration. Masks should fit snuggly over the nose and mouth. For this reason, masks that have a flexible nose piece and can be secured to the head with string ties or elastic are preferable.

Goggles provide barrier protection for the eyes. They should fit snuggly over and around the eyes. Goggles with anti-fog features will help maintain clarity of vision.

When skin protection, in addition to mouth, nose, and eye protection, is needed or desired, for example, when irrigating a wound or suctioning copious secretions, a face shield can be used as a substitute to wearing a mask or goggles. The face shield should cover the forehead, extend below the chin, and wrap around the side of the face.

Respiratory Protection

Respirators that filter the air before it is inhaled should be used for respiratory protection to protect healthcare workers from hazardous or infectious aerosols, such as Mycobacterium tuberculosis. The most commonly used respirators in healthcare settings are the N95, N99, or N100 particulate respirators.

Like other PPE, the selection of a respirator type must consider the nature of the exposure and risk involved. For example, N95 particulate respirators might be worn by personnel entering the room of a patient with infectious tuberculosis. However, if a bronchoscopy is performed on the patient, the healthcare provider might wear a higher level of respiratory protection, such as a powered air-purifying respirator or PAPR.

Prior the use of a respirator, it is important to undergo a medical evaluation determining the safety of wearing a respirator, fit testing to determine the appropriate size and type, training on how and when to use a respirator and finally fit checking before using it to ensure a proper seal. 

Sequence for Donning PPE

  1. Gown or apron.
  2. Mask or respirator.
  3. Goggles or face shields.
  4. Gloves.

However, the combination of PPE used, and therefore the sequence for donning, will be determined by the precautions that need to be taken.

Sequence for Removing PPE

  1. Gloves
  2. Face shield or goggles
  3. Gown
  4. Mask or respirator

The sequence for removing PPE is intended to limit opportunities for self-contamination. The gloves are considered the most contaminated pieces of PPE and are therefore removed first[2]. Below is a video that demonstrates donning and removing PPE.

The Location for Removing PPE

This depends on the amount and type of PPE worn and the category of isolation a patient is on, if applicable. If only gloves are worn as PPE, it is safe to remove and discard them in the patient room. When a gown or full PPE is worn, PPE should be removed at the doorway or in an anteroom. Respirators should always be removed outside the patient room, after the door is closed. Hand hygiene should be performed after all PPE is removed.

There is a risk of contamination of skin and clothes during removal of contaminated gloves or gowns. It is important to pay attention on the method of removing PPE to avoid contamination and disease transmission. Educating healthcare workers with the correct way of removing PPE by practice in removal of contaminated PPE with providing immediate visual feedback can reduce the risk of contamination of skin and clothes during removal of PPE[3].

Hand Hygiene

Hand hygiene is the cornerstone of preventing infection transmission. You should perform hand hygiene immediately after removing PPE. If your hands become visibly contaminated during PPE removal, wash hands before continuing to remove PPE. Wash your hands thoroughly with soap and warm water or, if hands are not visibly contaminated, use an alcohol-based hand rub. Below is a video that demonstrates the steps of hand hygiene.



  1. Loibner M, Hagauer S, Schwantzer G, Berghold A, Zatloukal K. Limiting factors for wearing personal protective equipment (PPE) in a health care environment evaluated in a randomised study. PloS one. 2019 Jan 22;14(1):e0210775.
  2. Cdcgov. Cdcgov. [Online]. Available from: [Accessed 21 April 2019].
  3. Tomas ME, Kundrapu S, Thota P, Sunkesula VC, Cadnum JL, Mana TS, Jencson A, O’donnell M, Zabarsky TF, Hecker MT, Ray AJ. Contamination of health care personnel during removal of personal protective equipment. JAMA internal medicine. 2015 Dec 1;175(12):1904-10.