Whitlow is a very painful and infectious viral disease of the thumb and fingertips. Rarely, it infects the toes and nail cuticle.  It is a self-limiting disease and it is of two types - Herpetic Whitlow and Melanotic Whitlow. Herpetic whitlow is more prevalent of the two. It is a disease of the hand.
Mechanism of Injury / Pathological Process
Herpetic whitlow is caused by the Herpetic Simplex Virus (HSV). HSV is of two types - type 1 and type 2.  They are both known to cause whitlow. Herpetic whitlow is caused when a wounded and exposed skin comes in contact with body fluids contaminated with HSV. It may also be caused by bacterial fingertip infection. 
Risk factors include;
- Human Immunodeficiency Virus (HIV) infection
- Nail biting habit
- Wounded finger with exposed skin surface
- Career in health care profession
The finger may present with; 
- Itchy feeling
- Burning sensation
- Redness, warmth or swelling
The body may present generally with; 
- Blisters and sores on other parts of the body
- Enlarged lymph nodes in the arm
High fever (temperature over 101°F) and confusion/lack of consciousness may indicate serious infection/progression of the disease.
Management / Interventions
Although, there is no known cure of the disease and the disease is a self-limiting one, therefore, it usually resolve within two to three weeks. However, certain measures may be undertaken to improve the symptoms. These include; 
- Topical anaesthetics to reduce pain and itching
- Antiviral medications
- Analgesics to reduce pain and fever (if present)
Not much research work has been done on Physiotherapy and Whitlow.
Untreated whitlow can come with serious complications which include; 
- Pain and discomfort
- Spread of infection
- Skin ulcerations and infections
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- Lloyd WC. Whitlow. Available from; https://www.healthgrades.com/right-care/infections-and-contagious-diseases/whitlow (Accessed 19/Oct/2020)
- Ismailov TA, Yevdulov OV, Khazamova MA, Gidurimova DA. Experimental Investigations of Thermoelectric Device for the Therapy of Whitlow. Journal of Thermoelectricity. 2013;4:78-84