Vitamin D and the Effect on Mental Health: Difference between revisions
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== Calcitrol == | == Calcitrol == | ||
The main function of calcitrol is its involvement with the synthesis and degradation of neurotransmitters, plays an important role in regulating various neurotrophic factors, and is an antioxidative defense mechanism for the brain. | |||
Calcitrol binds to a specific ligand, the Vitamin D receptor (VDR), which affects the gene expression of various target genes. VDR is located within the Central Nervous System (CNS), and the necessary enzymes and receptors spread throughout the human brain. the Viamin D endocrine system acts within the CNS. | |||
Clcitrol activates the gene expression of tyrosine hydroxylase, which increases the use of dopamine, adrenaline, and noradrenaline. | |||
== Possible Negative Effects == | == Possible Negative Effects == | ||
Latest revision as of 04:22, 30 June 2024
Original Editor - Kapil Narale
Top Contributors - Kapil Narale
Introduction[edit | edit source]
It is known that sunlight, warm temperatures, and the spring and summer seasons are associated with positive feelings and happiness. Dark, gloomy environments, associated with misery and fear, was associated with rickets. This is when Vitamin D was discovered. Vitamin D was discovered and identified in the 1920s. This was used as a remedy and treatment for rickets, which occurred with minimal sunlight exposure. As a prevention measure more sunlight exposure was needed. The prevention of rickets, encouraged the necessity of increased sunlight exposure. [1]
Calcitrol is the active Vitamin D hormone, which affect the neurotransmitters and neurotrophic factors that may lead to mental disorders. Vitamin D receptors and metabolites are present in the Central Nervous System. Vitamin D deficiency can be a cause for mental disorders. [1]
Calcitrol[edit | edit source]
The main function of calcitrol is its involvement with the synthesis and degradation of neurotransmitters, plays an important role in regulating various neurotrophic factors, and is an antioxidative defense mechanism for the brain.
Calcitrol binds to a specific ligand, the Vitamin D receptor (VDR), which affects the gene expression of various target genes. VDR is located within the Central Nervous System (CNS), and the necessary enzymes and receptors spread throughout the human brain. the Viamin D endocrine system acts within the CNS.
Clcitrol activates the gene expression of tyrosine hydroxylase, which increases the use of dopamine, adrenaline, and noradrenaline.
Possible Negative Effects[edit | edit source]
With an increased exposure to sunlight and solar radiation, there is a possibility of skin cancer, especially malignant melanoma, in the long term. With the change of minimsing exposure to sunlight, there was a noted increased prevalence of major depressive disorder in the US and Europe, especially among children and adolescents. There can also be an increased prevalence of autism spectrum disorder. [1]
Resources[edit | edit source]
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