Liver Function Tests: Difference between revisions

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== Introduction ==
== Introduction ==
Groups of blood tests performed to know the condition of a liver of a patient are known as Liver function tests (LFT) or liver panel or hepatic function panel or hepatic panel.<ref>Teshome G, Ambachew S, Fasil A, Abebe M. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803769/ Prevalence of liver function test abnormality and associated factors in type 2 diabetes mellitus: a comparative cross-sectional study]. Ejifcc. 2019 Oct;30(3):303.</ref>
Groups of blood tests performed to know the condition of a liver of a patient are known as liver function tests (LFT) or liver panel or hepatic function panel or hepatic panel.<ref>Teshome G, Ambachew S, Fasil A, Abebe M. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803769/ Prevalence of liver function test abnormality and associated factors in type 2 diabetes mellitus: a comparative cross-sectional study]. Ejifcc. 2019 Oct;30(3):303.</ref>


== Components of Liver Function Tests ==
== Components of Liver Function Tests ==

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Introduction[edit | edit source]

Groups of blood tests performed to know the condition of a liver of a patient are known as liver function tests (LFT) or liver panel or hepatic function panel or hepatic panel.[1]

Components of Liver Function Tests[edit | edit source]

Alanine Transaminase; Normal value: 0-45 IU/L

Aspartate Transaminase; Normal value: 0-35 IU/L

Causes of raised transaminases:
  • Alcohol.
  • Medications: non-steroidal anti-inflammatory drugs, antibiotics, HMG Co-A-reductase inhibitors, antiepileptic drugs, antituberculous drugs, herbal medications, illicit drug use.
  • Non-alcoholic steatohepatosis.
  • Chronic hepatitis B and C.
  • Autoimmune diseases.
  • Hemochromatosis.
  • Wilson's disease.
  • Congestive cardiac failure and ischaemic hepatitis.
  • ɑ1-Antitrypsin deficiency.
  • Coeliac disease.
  • Endocrine disease: hypothyroidism, Addison's disease.
  • Diseases of striate muscle.
  • Glycogen storage diseases.

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References[edit | edit source]