Transverse Myelitis
Original Editor - Wendy Walker
Lead Editors Wendy Walker
Introduction
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Transverse Myelitis (TM), AKA Acute Transverse Myelitis (ATM) is a rare neurological disorder of the spinal cord, caused by inflammation and occurring across one spinal segment, leading to severe motor, sensory and autonomic dysfunction[1].
The incidence of TM is 1 (severe) to 8 (mild) cases/million per year[2].
Mechanism of Injury / Pathological Process
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The mechanism of injury is inflammation of the spinal cord causing damage to the myelin sheath of the nerves.
Clinical Presentation[edit | edit source]
- Sensory, motor, or autonomic dysfunction attributable to the spinal cord
- Bilateral signs and/or symptoms
- Clearly defined sensory level
The symptoms of TM include muscle weakness, paralysis, parasthesia, neuropathic pain, spasticity, as well as bladder, bowel and sexual dysfunction. - See more at: http://www.myelitis.org.uk/symptoms-and-diagnosis.html#sthash.ZRv8wney.dpuf
There is tremendous variability in the presentation of symptoms, which are based on the level of the spinal cord affected and on the severity of the damage to the myelin and the neurons in the spinal cord.
Diagnostic Procedures[edit | edit source]
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Outcome Measures[edit | edit source]
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Management / Interventions
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Differential Diagnosis
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The most common etiologies to be distinguished from idiopathic acute transverse myelitis are:
parainfectious myelitis
NMO (Devic's disease)
myelitis related to systemic disease, such as systemic lupus erythematosis
Key Evidence[edit | edit source]
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Resources
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Case Studies[edit | edit source]
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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