The influence of human growth hormone (HGH) on physiologic processes and exercise

Introduction
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Muscular[edit | edit source]

Athletes ==

HGH injections and supplements are widely abused by athletes to enhance performance. Nevertheless, there is not enough definititive evidence that HGH improves performance[1]One study investigated the impact growth hormones have on body composition and measurable performance in recreational athletes[2]. The authors argued that growth hormone injections increase athletic exercise performance when given alone or with testosterone. In addition, participants that received growth hormones retained more body fluid and frequent joint pain than control group.

Older Adults[edit | edit source]

HGH injections are not only used for athletes, but for the older population as well. One study analyzed the impact of recombinant human growth hormones and testosterone injections on aerobic and anaerobic fitness, body mass, and lipid profile in adult men [3]. The data demonstrates that recombinant human growth hormones and testosterone injections significantly increased aerobic and anaerobic capacity, led to changes in body compositions, and decreased total body fat and increased free-fat muscle. In another study, the authors analyzed whether treatment with testosterone and recombinant human growth hormones would increase muscle strength and mass in older adult patients[4]. The authors found that recombinant human growth hormones are connected with fluid preservation and improvements in muscle mass and strength that would translate into better aerobic exercise performance.  

  1. Saugy, M., Robinson, N., Saudan, C., Baume, N., Avois, L., Mahgin, P. (2006). Human growth hormone doping in sport. British Journal of Sports Medicine, 40, 135-139.
  2. Meinhardt, U., Nelson, A. E., Hansen, J. L., Birzniece, V., Clifford, D., Leung, K., . . . Ho, K. K. (2010). The effects of growth hormone on body composition and performance in recreational athletes. Annals of Internal Medicine, 152, 568-577.
  3. Zajac, A., Wilk, M., Socha, T., Maszczyk, A., and Chycki, J. (2014). Effects of growth hormone and testosterone therapy on aerobic and anaerobic fitness, body composition and lipoprotein profile in middle-aged men. Annal of Agricultural and Environmental Medicine, 21(1), 156-160.
  4. Schroeder, E. T., He, J., Yarasheski, K. E., Binder, E. F., Castaneda-Sceppa, C., Bhasin, S., . . . Sattler, F. R. (2011). Value of measuring muscle performance to assess changes in lean mass with testosterone and growth hormone supplementation. Europe Journal of Applied Physiology, 112, 1123-1131.