Liver Function Tests

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Introduction[edit | edit source]

Groups of blood tests performed to know the condition of a liver of a patient are known as liver function tests (LFT) or liver panel or hepatic function panel or hepatic panel.[1]

Components of Liver Function Tests[edit | edit source]

Alanine Transaminase; Normal value: 0-45 IU/L

Aspartate Transaminase; Normal value: 0-35 IU/L[2]

Causes of raised transaminases:
  • Alcohol.
  • Medications: non-steroidal anti-inflammatory drugs, antibiotics, HMG Co-A-reductase inhibitors, antiepileptic drugs, antituberculous drugs, herbal medications, illicit drug use.
  • Non-alcoholic steatohepatosis.
  • Chronic hepatitis B and C.
  • Autoimmune diseases.
  • Hemochromatosis.
  • Wilson's disease.
  • Congestive cardiac failure and ischaemic hepatitis.
  • ɑ1-Antitrypsin deficiency.
  • Coeliac disease.
  • Endocrine disease: hypothyroidism, Addison's disease.
  • Diseases of striate muscle.
  • Glycogen storage diseases.[3]

Sub Heading 3[edit | edit source]

Resources[edit | edit source]

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References[edit | edit source]

  1. ↑ Teshome G, Ambachew S, Fasil A, Abebe M. Prevalence of liver function test abnormality and associated factors in type 2 diabetes mellitus: a comparative cross-sectional study. Ejifcc. 2019 Oct;30(3):303.
  2. ↑ Lala V, Goyal A, Bansal P, Minter D. Liver function tests. StatPearls. 2020 Apr 28.
  3. ↑ Limdi JK, Hyde GM. Evaluation of abnormal liver function tests. Postgraduate medical journal. 2003 Jun 1;79(932):307-12.
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