Acute Care Management of a Patient with Multiple Trauma: Difference between revisions

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== Introduction ==
== Introduction ==
Early acute care rehabilitation initiated on the Intensive Care Unit has a positive effect on patient's functional status, muscle strength, mechanical ventilation duration, walking ability at discharge, and health quality of life.<ref name=":0">Arias-Fernández P, Romero-Martin M, Gómez-Salgado J, Fernández-García D. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127491/pdf/jpts-30-1193.pdf Rehabilitation and early mobilization in the critical patient: systematic review]. J Phys Ther Sci. 2018 Sep;30(9):1193-1201. </ref>Patients with multiple trauma must often overcome the effects of the use of mechanical ventilation, administration of drugs, sedatives, analgesics, and drugs to control their anxiety and agitation. <ref name=":0" />The secondary complications may include joint contractures, thromboembolism, pressure ulcers, pneumonia, difficulties  with weaning off the ventilator, delirium, and development of disabilities. <ref name=":0" />There is a social impact of a prolonged hospitalisation with increased days without income, inability to provide for family and inability to fulfill previously established social roles. This article provides an overview for the  the  
Early acute care rehabilitation initiated in the Intensive Care Unit (ICU) can positively affect a patient's functional status, muscle strength, time spent on mechanical ventilation, walking ability at discharge, and health-related quality of life.<ref name=":0">Arias-Fernández P, Romero-Martin M, Gómez-Salgado J, Fernández-García D. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127491/pdf/jpts-30-1193.pdf Rehabilitation and early mobilization in the critical patient: systematic review]. J Phys Ther Sci. 2018 Sep;30(9):1193-1201. </ref><ref>Zhang L, Hu W, Cai Z, Liu J, Wu J, Deng Y, Yu K, Chen X, Zhu L, Ma J, Qin Y. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6776357/pdf/pone.0223185.pdf Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis.] PLoS One. 2019 Oct 3;14(10):e0223185.</ref> Patients with multiple traumas who require critical care are often exposed to interventions that "promote long periods of immobilization",<ref name=":0" /> such as mechanical ventilation, sedatives, analgesics, and drugs to control anxiety and agitation.<ref name=":0" /> Patients in ICU are at risk of intensive care unit-acquired weakness (ICU-AW), which is associated with a number of complications, including joint contractures, thromboembolism, pressure ulcers, atelectasis, pneumonia, an extended period weaning off mechanical ventilation, delirium, and the development of disabilities.<ref name=":0" /> Prolonged hospitalisation also has a significant social impact, including increased days without income, inability to provide for family and an inability to fulfil previously established social roles. This article provides an overview of the assessment of a patient with a complex injury in an acute care setting. 
 
== Multiple Trauma ==
<blockquote>"Major trauma refers to physical injury or a combination of injuries where there is a strong possibility of death or disability and is commonly defined using an Injury Severity Score."<ref>Naess HL, Vikane E, Wehling EI, Skouen JS, Bell RF, Johnsen LG. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853396/pdf/main.pdf Effect of Early Interdisciplinary Rehabilitation for Trauma Patients: A Systematic Review.] Arch Rehabil Res Clin Transl. 2020 Jun 25;2(4):100070.</ref></blockquote>The Injury Severity Score allows one to describe the severity of injury in a trauma patient. It includes assessing 6 body systems that receive scores according to the Abbreviated Injury Scale. A score ''greater than 15'' defines major trauma. <ref>Javali RH, Krishnamoorthy, Patil A, Srinivasarangan M, Suraj, Sriharsha. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487611/pdf/ijccm-23-73.pdf Comparison of Injury Severity Score, New Injury Severity Score, Revised Trauma Score and Trauma and Injury Severity Score for Mortality Prediction in Elderly Trauma Patients.] Indian J Crit Care Med. 2019 Feb;23(2):73-77. </ref>  
 
== Multidisciplinary Team Approach ==
Patients with complex orthopaedic trauma admitted to the hospital benefit from early rehabilitation interventions to prevent complications and promote recovery. The acute care trauma and rehabilitation teams form an multidisciplinary team when the team members work together in treatment and goal setting. The optimal approach for the management of a patient with complex orthopaedic trauma requires clinical collaboration between the members of the multidisciplinary team to ensure the successful integration of medical, rehabilitative, psychosocial, and financial resources available across various specialities. The care of the patient with multiple orthopaedic injuries often necessitates the involvement of the orthopaedic surgeon, nursing staff, physiotherapist, occupational therapist, respiratory therapist, speech-language pathologist, and social worker. 
 
== Patient Management in the Intensive Care Unit ==
Before initiating the assessment, the physiotherapist must obtain information that will help to determine the patient's appropriateness for physiotherapy intervention. This is completed via chart review and discussion with the members of the team.
 
=== Chart Review ===
The patient's chart should provide the following information:<ref name=":2">Downey R. Case Discussion on the Continuum of Care for a Patient with Multiple Trauma. Plus Course 2024</ref>
* Movement precautions and weight-bearing restrictions
* Plan to manage fractures to determine the patient's functional mobility progression
**Patients at a high risk of complications receive early temporary stabilisation followed by delayed definitive fixation<ref name=":1">Bach JA, Leskovan JJ, Scharschmidt T, Boulger C, Papadimos TJ, Russell S, Bahner DP, Stawicki SP. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364767/?report=printable The right team at the right time - Multidisciplinary approach to multi-trauma patient with orthopedic injuries]. Int J Crit Illn Inj Sci. 2017 Jan-Mar;7(1):32-37.</ref>
*Information on medical stability
**Ventilator settings and plans for extubation
**Additional complications
**Lab values and vitals
***Haematocrit
***Haemoglobin
***Markers for acute infection: C-reactive protein (CRP) and procalcitonin (PCT) <ref>Binnie A, Lage J, Dos Santos CC. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152028/pdf/main.pdf How can biomarkers be used to differentiate between infection and non-infectious causes of inflammation?] Evidence-Based Practice of Critical Care. 2020:319–324.e1.</ref>
**Vitals
***Blood pressure, heart rate and rhythm, temperature, and respiratory rate
**Trends in arterial blood gases (ABG)
***pH, pCO2, pO2, bicarbonate (HCO3), base excess (BE), Lactate <ref>Langer T, Brusatori S, Gattinoni L. [[Langer T, Brusatori S, Gattinoni L. Understanding base excess (BE): merits and pitfalls. Intensive Care Med. 2022 Aug;48(8):1080-1083.|Understanding base excess (BE): merits and pitfalls]]. Intensive Care Med. 2022 Aug;48(8):1080-1083.</ref>
*Level of sedation
**[[Richmond Agitation-Sedation Scale (RASS)|Richmond Agitation Sedation Scale]] (RASS)
***Allows for tracking the level of sedation
***Ranges between +4 and -5
This optional video demonstrates how to use the Richmond Agitation and Sedation Scale:{{#ev:youtube|v=-jnUsQIzSUs|300}}<ref>ICU REACH. Richmond Agitation-Sedation Scale (RASS). Available from: https://www.youtube.com/watch?v=-jnUsQIzSUs [last accessed 26/4/2024]</ref>
 
*Members of the Multidisciplinary Team
**May include primary physicians, surgeons, neurologists, pulmonologists, physiotherapists, occupational therapists, nursing staff, social workers, case management, and speech therapy
 
=== Multidisciplinary Team Discussions ===
Frequent discussions with multidisciplinary team members allow for the following:<ref name=":2" />
 
* To establish a team communication plan
* To understand social factors impacting discharge planning
* To obtain information about the patient's access to resources
* Coordinate with nursing staff the timing of therapy sessions to optimise patient's medication level
* To gather additional information on the patient's cognition, agitation, and ability to follow commands
* To update information about the patient's ability to participate, haemodynamic response to activity, and plan for ongoing medical interventions
 
=== Interdisciplinary Assessment ===
To increase the accuracy of the assessment, the clinician should (1) determine the patient's level of confusion and (2) assess the patient's ability to follow basic commands and establish consistent and reliable communication with the patient:<ref name=":2" />
 
# Determine the patient's level of confusion:<ref>Heslot C, Azouvi P, Perdrieau V, Granger A, Lefèvre-Dognin C, Cogné M. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604759/pdf/jcm-11-06224.pdf A Systematic Review of Treatments of Post-Concussion Symptoms.] J Clin Med. 2022 Oct 21;11(20):6224. </ref>
#* The Confusion Assessment Method for the ICU (CAM-ICU)<ref>Miranda F, Arevalo‐Rodriguez I, Díaz G, Gonzalez F, Plana MN, Zamora J, Quinn TJ, Seron P. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513664/pdf/CD013126.pdf Confusion Assessment Method for the intensive care unit (CAM‐ICU) for the diagnosis of delirium in adults in critical care settings.] Cochrane Database Syst Rev. 2018 Sep 10;2018(9):CD013126.</ref>
#* Alert, Voice, Pain, Unresponsive scale (AVPU)<ref>Romanelli D, Farrell MW. AVPU Scale. [Updated 2023 Apr 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538431/ [last access 26.4.2024]</ref>


== Sub Heading 2 ==


== Sub Heading 3 ==
This optional video demonstrates how to use the Confusion Assessment Method for the ICU (CAM-ICU):{{#ev:youtube|v=slCX_6iV0fg|300}}<ref>Critical Care Nursing 101. Confusion Assessment Method (CAM-ICU). Available from: https://www.youtube.com/watch?v=slCX_6iV0fg [last accessed 26/4/2024]</ref>
 
This optional video demonstrates how to use the Alert, Voice, Pain, Unresponsive scale (AVPU):
 
{{#ev: youtube|v=olToUEk0Ayo|300}}<ref>Top Hat Tutorials. The AVPU Scale. Available from: https://www.youtube.com/watch?v=olToUEk0Ayo[last accessed 26/4/2024]</ref>
 
2. Establish consistent and reliable communication with the patient:
 
** A head nod, a head shake, blinking for a yes or for a no
** Picture communication boards
** Letter spelling boards
 
=== Body Systems Assessment ===
Table 1 provides a summary of the body systems assessment to be completed during physiotherapy intervention:
{| class="wikitable"
|+Table 1. Body Systems Assessment
!'''Body Systems'''
!'''What to assess?'''
|-
|Cardiovascular
system
|
* Check blood pressure and heart rate response with activity:
** The transition from a supine to a sitting position
** The transition from a sitting to a standing position
|-
|Pulmonary system
|
* Check oxygen response and changes in respiratory rate with activity
|-
|Integumentary system
|
* Assess the skin around the surgical site
* Look for signs and symptoms of the infection
* Assess for pressure injuries
|-
|Musculoskeletal system
|
* A general range of motion and strength assessment, if appropriate
** It may be hypothesised based on the patient's social history (type of work)
** It may be completed based on the observation of the patient's moving
|}
 
=== Outcome Mesures ===
The following outcome measures can help with tracking changes in a patient's functional mobility over time:
 
* [[Perme Intensive Care Unit Mobility Score|Perme ICU Mobility Scale]]
* [[ICU Mobility Scale]]
 
=== Interdisciplinary Goals ===
# Increase tolerance for upright mobility
# Complete basic activities of daily living in a sitting
# Incorporate breathing technique with upright mobility
# Incorporate strategies for delirium prevention and delirium management
# Use alternative approaches to decrease agitation and increase patient's participation
# Incorporate positioning strategies for pressure sore prevention and pain and oedema reduction
# Family and friends education on delirium prevention strategies:<ref>Low Stimulation Environment Guideline. Available from https://craighospital.org/wp-content/uploads/sites/Educational-PDFs/852.LowStimulationGuidlines.pdf [last access 26.4.2024]</ref>
#* Perform frequent reorientation
#* Keep the lights on and the windows open during the daytime
#* Limit activities that require a lot of concentration
#* Limit the number of individuals speaking to a patient at a time
#* Limit external noises (close the door, turn off the television)
#* Provide mental breaks after periods of high stimulation
 
== Patient Management post-Intensive Care Unit ==
After the patient's transfer from the intensive care unit to a general ward, the focus of physiotherapy intervention should include the following:
 
* Reassessment due to the changes in the patient's medical status
* Establishing specific goals with the patient
* Completing a systems review
* Increasing the patient's independence with functional mobility.
*Assessing the need for an assistive device
 
=== Interdisciplinary Assessment ===
The patient's assessment in the post-intensive care unit stay should include the following:
 
* Basic functional mobility, including bed mobility, transfers, and gait
* Outcome measures to track the patient's progress:
** [https://www.sralab.org/rehabilitation-measures/activity-measure-post-acute-care Activity Measure for Post-Acute Care "6-Clicks" Short Form] (AM-PAC "6-Clicks")<ref>Herbold J, Rajaraman D, Taylor S, Agayby K, Babyar S. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9482026/pdf/main.pdf Activity Measure for Post-Acute Care "6-Clicks" Basic Mobility Scores Predict Discharge Destination After Acute Care Hospitalization in Select Patient Groups: A Retrospective, Observational Study.] Arch Rehabil Res Clin Transl. 2022 Jul 16;4(3):100204. </ref>
*** Any provider can complete it
*** Allows increased communication and tracking of mobility between members of the interdisciplinary team
* Balance assessment
** [[Dynamic Gait Index]]
* Functional activity tolerance assessment
** [[2 Minute Walk Test|2-Minute Walk Test]] or a [[Six Minute Walk Test / 6 Minute Walk Test|6-Minute Walk]]
 
=== Interdisciplinary Goals ===
 
* To improve independence
* To improve activity tolerance
* To improve breathing mechanics and secretion management
* To ensure a safe return home
 
=== Interdisciplinary Interventions ===
The multidisciplinary team interventions focus on the following:
 
* Improving patient's functional mobility
* Patient's education regarding the continued need to progress weight-bearing
* Trials of the least restrictive devices
* Progressive ambulation
* Education on productive cough:
** Active cycle of breathing, huff coughing, incentive spirometer, inspiratory muscle training
* Education on continued post-concussive syndrome support strategies:
** Visual task reminders
** Taking cognitive breaks during the day
** Placing time limits on activities, especially those that require a lot of concentration or a lot of in-depth thought
*Interdisciplinary conversations to ensure a successful and safe discharge into the community
*Establishing follow-up care and reintegration into the community for the patient upon discharge from the acute care hospital


== Resources  ==
== Resources  ==
*bulleted list
*Al Hanna R, Amatya B, Lizama LE, Galea MP, Khan F. [https://medicaljournalssweden.se/jrm/article/view/3747/5806 Multidisciplinary rehabilitation in persons with multiple trauma: A systematic review.] J Rehabil Med. 2020 Oct 2;52(10):jrm00108.
*x
or
 
#numbered list
#x


== References  ==
== References  ==


<references />
<references />
[[Category:Course Pages]]
[[Category:SRSHS Course Pages]]
[[Category:Injury]]
[[Category:Rehabilitation]]

Latest revision as of 09:10, 4 May 2024

Original Editor - Rebecca Downey

Top Contributors - Ewa Jaraczewska and Jess Bell  

Introduction[edit | edit source]

Early acute care rehabilitation initiated in the Intensive Care Unit (ICU) can positively affect a patient's functional status, muscle strength, time spent on mechanical ventilation, walking ability at discharge, and health-related quality of life.[1][2] Patients with multiple traumas who require critical care are often exposed to interventions that "promote long periods of immobilization",[1] such as mechanical ventilation, sedatives, analgesics, and drugs to control anxiety and agitation.[1] Patients in ICU are at risk of intensive care unit-acquired weakness (ICU-AW), which is associated with a number of complications, including joint contractures, thromboembolism, pressure ulcers, atelectasis, pneumonia, an extended period weaning off mechanical ventilation, delirium, and the development of disabilities.[1] Prolonged hospitalisation also has a significant social impact, including increased days without income, inability to provide for family and an inability to fulfil previously established social roles. This article provides an overview of the assessment of a patient with a complex injury in an acute care setting.

Multiple Trauma[edit | edit source]

"Major trauma refers to physical injury or a combination of injuries where there is a strong possibility of death or disability and is commonly defined using an Injury Severity Score."[3]

The Injury Severity Score allows one to describe the severity of injury in a trauma patient. It includes assessing 6 body systems that receive scores according to the Abbreviated Injury Scale. A score greater than 15 defines major trauma. [4]

Multidisciplinary Team Approach[edit | edit source]

Patients with complex orthopaedic trauma admitted to the hospital benefit from early rehabilitation interventions to prevent complications and promote recovery. The acute care trauma and rehabilitation teams form an multidisciplinary team when the team members work together in treatment and goal setting. The optimal approach for the management of a patient with complex orthopaedic trauma requires clinical collaboration between the members of the multidisciplinary team to ensure the successful integration of medical, rehabilitative, psychosocial, and financial resources available across various specialities. The care of the patient with multiple orthopaedic injuries often necessitates the involvement of the orthopaedic surgeon, nursing staff, physiotherapist, occupational therapist, respiratory therapist, speech-language pathologist, and social worker.

Patient Management in the Intensive Care Unit[edit | edit source]

Before initiating the assessment, the physiotherapist must obtain information that will help to determine the patient's appropriateness for physiotherapy intervention. This is completed via chart review and discussion with the members of the team.

Chart Review[edit | edit source]

The patient's chart should provide the following information:[5]

  • Movement precautions and weight-bearing restrictions
  • Plan to manage fractures to determine the patient's functional mobility progression
    • Patients at a high risk of complications receive early temporary stabilisation followed by delayed definitive fixation[6]
  • Information on medical stability
    • Ventilator settings and plans for extubation
    • Additional complications
    • Lab values and vitals
      • Haematocrit
      • Haemoglobin
      • Markers for acute infection: C-reactive protein (CRP) and procalcitonin (PCT) [7]
    • Vitals
      • Blood pressure, heart rate and rhythm, temperature, and respiratory rate
    • Trends in arterial blood gases (ABG)
      • pH, pCO2, pO2, bicarbonate (HCO3), base excess (BE), Lactate [8]
  • Level of sedation

This optional video demonstrates how to use the Richmond Agitation and Sedation Scale:

[9]

  • Members of the Multidisciplinary Team
    • May include primary physicians, surgeons, neurologists, pulmonologists, physiotherapists, occupational therapists, nursing staff, social workers, case management, and speech therapy

Multidisciplinary Team Discussions[edit | edit source]

Frequent discussions with multidisciplinary team members allow for the following:[5]

  • To establish a team communication plan
  • To understand social factors impacting discharge planning
  • To obtain information about the patient's access to resources
  • Coordinate with nursing staff the timing of therapy sessions to optimise patient's medication level
  • To gather additional information on the patient's cognition, agitation, and ability to follow commands
  • To update information about the patient's ability to participate, haemodynamic response to activity, and plan for ongoing medical interventions

Interdisciplinary Assessment[edit | edit source]

To increase the accuracy of the assessment, the clinician should (1) determine the patient's level of confusion and (2) assess the patient's ability to follow basic commands and establish consistent and reliable communication with the patient:[5]

  1. Determine the patient's level of confusion:[10]
    • The Confusion Assessment Method for the ICU (CAM-ICU)[11]
    • Alert, Voice, Pain, Unresponsive scale (AVPU)[12]


This optional video demonstrates how to use the Confusion Assessment Method for the ICU (CAM-ICU):

[13]

This optional video demonstrates how to use the Alert, Voice, Pain, Unresponsive scale (AVPU):

[14]

2. Establish consistent and reliable communication with the patient:

    • A head nod, a head shake, blinking for a yes or for a no
    • Picture communication boards
    • Letter spelling boards

Body Systems Assessment[edit | edit source]

Table 1 provides a summary of the body systems assessment to be completed during physiotherapy intervention:

Table 1. Body Systems Assessment
Body Systems What to assess?
Cardiovascular

system

  • Check blood pressure and heart rate response with activity:
    • The transition from a supine to a sitting position
    • The transition from a sitting to a standing position
Pulmonary system
  • Check oxygen response and changes in respiratory rate with activity
Integumentary system
  • Assess the skin around the surgical site
  • Look for signs and symptoms of the infection
  • Assess for pressure injuries
Musculoskeletal system
  • A general range of motion and strength assessment, if appropriate
    • It may be hypothesised based on the patient's social history (type of work)
    • It may be completed based on the observation of the patient's moving

Outcome Mesures[edit | edit source]

The following outcome measures can help with tracking changes in a patient's functional mobility over time:

Interdisciplinary Goals[edit | edit source]

  1. Increase tolerance for upright mobility
  2. Complete basic activities of daily living in a sitting
  3. Incorporate breathing technique with upright mobility
  4. Incorporate strategies for delirium prevention and delirium management
  5. Use alternative approaches to decrease agitation and increase patient's participation
  6. Incorporate positioning strategies for pressure sore prevention and pain and oedema reduction
  7. Family and friends education on delirium prevention strategies:[15]
    • Perform frequent reorientation
    • Keep the lights on and the windows open during the daytime
    • Limit activities that require a lot of concentration
    • Limit the number of individuals speaking to a patient at a time
    • Limit external noises (close the door, turn off the television)
    • Provide mental breaks after periods of high stimulation

Patient Management post-Intensive Care Unit[edit | edit source]

After the patient's transfer from the intensive care unit to a general ward, the focus of physiotherapy intervention should include the following:

  • Reassessment due to the changes in the patient's medical status
  • Establishing specific goals with the patient
  • Completing a systems review
  • Increasing the patient's independence with functional mobility.
  • Assessing the need for an assistive device

Interdisciplinary Assessment[edit | edit source]

The patient's assessment in the post-intensive care unit stay should include the following:

Interdisciplinary Goals[edit | edit source]

  • To improve independence
  • To improve activity tolerance
  • To improve breathing mechanics and secretion management
  • To ensure a safe return home

Interdisciplinary Interventions[edit | edit source]

The multidisciplinary team interventions focus on the following:

  • Improving patient's functional mobility
  • Patient's education regarding the continued need to progress weight-bearing
  • Trials of the least restrictive devices
  • Progressive ambulation
  • Education on productive cough:
    • Active cycle of breathing, huff coughing, incentive spirometer, inspiratory muscle training
  • Education on continued post-concussive syndrome support strategies:
    • Visual task reminders
    • Taking cognitive breaks during the day
    • Placing time limits on activities, especially those that require a lot of concentration or a lot of in-depth thought
  • Interdisciplinary conversations to ensure a successful and safe discharge into the community
  • Establishing follow-up care and reintegration into the community for the patient upon discharge from the acute care hospital

Resources[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 Arias-Fernández P, Romero-Martin M, Gómez-Salgado J, Fernández-García D. Rehabilitation and early mobilization in the critical patient: systematic review. J Phys Ther Sci. 2018 Sep;30(9):1193-1201.
  2. Zhang L, Hu W, Cai Z, Liu J, Wu J, Deng Y, Yu K, Chen X, Zhu L, Ma J, Qin Y. Early mobilization of critically ill patients in the intensive care unit: A systematic review and meta-analysis. PLoS One. 2019 Oct 3;14(10):e0223185.
  3. Naess HL, Vikane E, Wehling EI, Skouen JS, Bell RF, Johnsen LG. Effect of Early Interdisciplinary Rehabilitation for Trauma Patients: A Systematic Review. Arch Rehabil Res Clin Transl. 2020 Jun 25;2(4):100070.
  4. Javali RH, Krishnamoorthy, Patil A, Srinivasarangan M, Suraj, Sriharsha. Comparison of Injury Severity Score, New Injury Severity Score, Revised Trauma Score and Trauma and Injury Severity Score for Mortality Prediction in Elderly Trauma Patients. Indian J Crit Care Med. 2019 Feb;23(2):73-77.
  5. 5.0 5.1 5.2 Downey R. Case Discussion on the Continuum of Care for a Patient with Multiple Trauma. Plus Course 2024
  6. Bach JA, Leskovan JJ, Scharschmidt T, Boulger C, Papadimos TJ, Russell S, Bahner DP, Stawicki SP. The right team at the right time - Multidisciplinary approach to multi-trauma patient with orthopedic injuries. Int J Crit Illn Inj Sci. 2017 Jan-Mar;7(1):32-37.
  7. Binnie A, Lage J, Dos Santos CC. How can biomarkers be used to differentiate between infection and non-infectious causes of inflammation? Evidence-Based Practice of Critical Care. 2020:319–324.e1.
  8. Langer T, Brusatori S, Gattinoni L. Understanding base excess (BE): merits and pitfalls. Intensive Care Med. 2022 Aug;48(8):1080-1083.
  9. ICU REACH. Richmond Agitation-Sedation Scale (RASS). Available from: https://www.youtube.com/watch?v=-jnUsQIzSUs [last accessed 26/4/2024]
  10. Heslot C, Azouvi P, Perdrieau V, Granger A, Lefèvre-Dognin C, Cogné M. A Systematic Review of Treatments of Post-Concussion Symptoms. J Clin Med. 2022 Oct 21;11(20):6224.
  11. Miranda F, Arevalo‐Rodriguez I, Díaz G, Gonzalez F, Plana MN, Zamora J, Quinn TJ, Seron P. Confusion Assessment Method for the intensive care unit (CAM‐ICU) for the diagnosis of delirium in adults in critical care settings. Cochrane Database Syst Rev. 2018 Sep 10;2018(9):CD013126.
  12. Romanelli D, Farrell MW. AVPU Scale. [Updated 2023 Apr 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538431/ [last access 26.4.2024]
  13. Critical Care Nursing 101. Confusion Assessment Method (CAM-ICU). Available from: https://www.youtube.com/watch?v=slCX_6iV0fg [last accessed 26/4/2024]
  14. Top Hat Tutorials. The AVPU Scale. Available from: https://www.youtube.com/watch?v=olToUEk0Ayo[last accessed 26/4/2024]
  15. Low Stimulation Environment Guideline. Available from https://craighospital.org/wp-content/uploads/sites/Educational-PDFs/852.LowStimulationGuidlines.pdf [last access 26.4.2024]
  16. Herbold J, Rajaraman D, Taylor S, Agayby K, Babyar S. Activity Measure for Post-Acute Care "6-Clicks" Basic Mobility Scores Predict Discharge Destination After Acute Care Hospitalization in Select Patient Groups: A Retrospective, Observational Study. Arch Rehabil Res Clin Transl. 2022 Jul 16;4(3):100204.