Double Crush Syndrome
Introduction[edit | edit source]
- The double crush hypothesis was first formulated in 1973 and states that axons that have been compressed at one site become especially susceptible to damage at another site.
- This theory was originally described by Upton (1973) in a study of 115 patients.
- The existence of double crush syndrome was further substantiated by Massey's (1981) study of nineteen cases of carpal tunnel syndrome co-existing with a cervical radiculopathy.
Hypothesis[edit | edit source]
- It is suggested that compression of an axon at one location makes it more sensitive to effects of compression in another location,because of impaired axoplasmic flow.
- Hypothetically, two lesions with little or no independent clinical ramifications, when combined, lead to appearance or magnification of symptoms