End Organ: Difference between revisions

No edit summary
No edit summary
Line 7: Line 7:
An end organ is the last  organ affected in a chain of events, for instance a disease process.  
An end organ is the last  organ affected in a chain of events, for instance a disease process.  


Examples are the liver, brain or kidney, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.
Examples are the liver, brain, kidney or heart, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.


== Sub Heading 2 ==
== Detection ==
Timely detection of end organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients suffering from arterial hypertension ([[/www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/#R2|2]]). Classical indicators of hypertensive end organ damage include the following: vascular and hemorrhagic stroke, retinopathy, coronary heart disease/myocardial infarction and heart failure, proteinuria and renal failure and in the vasculature, atherosclerotic change including the development of stenoses and aneurysms.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref>
Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.  


* Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
Classical pointers for end organ damage include:
* Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
 
* Similar to arterial hypertension and obesity, type 2 diabetes mellitus is associated with target organ damage
* Stoke, vascular and hemorrhagic
* Retinopathy
* Coronary heart disease/myocardial infarction and heart failure
* Proteinuria
* Renal failure
* Atherosclerotic change eg stenoses and aneurysms in the blood vessels.<ref>Schmieder RE. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ End organ damage in hypertension.] Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)</ref>
 
== Risk Factors ==
Many and varied and include:
 
# Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
# Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
# Type 2 diabetes mellitus is associated with target organ damage


== Sub Heading 3 ==
== Sub Heading 3 ==

Revision as of 08:39, 9 May 2024

Original Editor - User Name

Top Contributors - Lucinda hampton  

Introduction[edit | edit source]

An end organ is the last organ affected in a chain of events, for instance a disease process.

Examples are the liver, brain, kidney or heart, and are ultimately affected by a chronic or progressive disease or condition like diabetes or hypertension.

Detection[edit | edit source]

Timely detection of end organ damage and secondary diseases are the main determining factors of cardiovascular prognosis in patients suffering from arterial hypertension.

Classical pointers for end organ damage include:

  • Stoke, vascular and hemorrhagic
  • Retinopathy
  • Coronary heart disease/myocardial infarction and heart failure
  • Proteinuria
  • Renal failure
  • Atherosclerotic change eg stenoses and aneurysms in the blood vessels.[1]

Risk Factors[edit | edit source]

Many and varied and include:

  1. Arterial hypertensive is a risk factor for end organ damage, and can now be diagnosed early and reversed with specific and aggressive treatment.
  2. Obesity is a risk factor for development of target organ damage, due to development of hypertension, and needs adressing early for prevention of such.
  3. Type 2 diabetes mellitus is associated with target organ damage

Sub Heading 3[edit | edit source]

Resources[edit | edit source]

  • bulleted list
  • x

or

  1. numbered list
  2. x

References[edit | edit source]

  1. Schmieder RE. End organ damage in hypertension. Deutsches Ärzteblatt International. 2010 Dec;107(49):866.Available:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011179/ (accessed 9.5.2024)