Grades and Levels of Evidence
Original Editor - Tyler Shultz
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Discussion & Background[edit | edit source]
Levels of Evidence[edit | edit source]
| Level |
Therapy/Prevetion, Aetiology/Harm |
Prognosis |
Diagnosis |
Differential Diagnosis |
Economic and Descision Analysis |
| 1A |
SR (with homogeneity) of RCTs |
SR (with homogeneity) of inception cohort studies; CDR validated in different populations |
SR (with homogeneity) of Level 1 diagnostic studies; CDR with 1b studies from different clinical centres |
SR (with homogeneity) of prospective cohort studies |
SR (with homogeneity) of Level 1 economic studies |
| 1B |
Individual RCT (with narrow Confidence Interval) |
Individual inception cohort study with > 80% follow-up; CDR validated in a single population |
Validating cohort study with good reference standards; or CDR tested within one clinical centre |
Prospective cohort study with good follow-up |
Analysis based on clinically sensible costs or alternatives; systematic review(s) of the evidence; and including multi-way sensitivity analyses |
| 1C |
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| 2A |
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| 2B |
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| 2C |
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| 3A |
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| 3B |
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| 4 |
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| 5 |
Grades of Evidence[edit | edit source]
Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
