Modic Changes: Difference between revisions

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== Clinically Relevant Anatomy may  ==
== Clinically Relevant Anatomy may  ==


Modic changes (MC) are bone marrow lesions seen within a vertebral body on magnetic resonance imaging (MRI), suggestive of being associated with [https://www.physio-pedia.com/Low_Back_Pain low back pain (LBP)]. <ref name=":0">MC Fu, ML Webb, RA Buerba, WE Neway, JE Brown… - The Spine Journal, 2016</ref> Their presence in clients receiving physiotherapy for low back pain may be of significance when discussing prognosis and benefits of exercise therapy. <br>  
Modic changes (MC) are bone marrow lesions seen within a vertebral body on magnetic resonance imaging (MRI), suggestive of being associated with [https://www.physio-pedia.com/Low_Back_Pain low back pain (LBP)]. <ref name=":0">Mok FP, Samartzis D, Karppinen J, Fong DY, Luk KD, Cheung KM. Modic changes of the lumbar spine: prevalence, risk factors, and association with disc degeneration and low back pain in a large-scale population-based cohort. The Spine Journal. 2016 Jan 1;16(1):32-41.</ref> Their presence in clients receiving physiotherapy for low back pain may be of significance when discussing prognosis and benefits of exercise therapy. <br>  


== Mechanism of Injury / Pathological Process<br>  ==
== Mechanism of Injury / Pathological Process<br>  ==
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Proposed risk factors include:
Proposed risk factors include:
* Body mass index (BMI) ranking of overweight or obese
* Body mass index (BMI) ranking of overweight or obese <ref name=":1">Määttä JH, Wadge S, MacGregor A, Karppinen J, Williams FM. ISSLS prize winner: vertebral endplate (Modic) change is an independent risk factor for episodes of severe and disabling low back pain. Spine. 2015 Aug 1;40(15):1187-93.</ref><ref name=":0" />


* Smoking <br>  
* Smoking <br>  
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== References  ==
== References  ==


<references group="MC Fu, ML Webb, RA Buerba, WE Neway, JE Brown… - The Spine Journal, 2016" /><ref name=":0" /><ref>W Xia, C Liu, S Duan, S Xu, K Wang, Z Zhu, H Liu - PloS one, 2018</ref>
<references group="MC Fu, ML Webb, RA Buerba, WE Neway, JE Brown… - The Spine Journal, 2016" /><ref name=":0" /><ref>W Xia, C Liu, S Duan, S Xu, K Wang, Z Zhu, H Liu - PloS one, 2018</ref><ref name=":1" />

Revision as of 20:14, 14 June 2018

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Clinically Relevant Anatomy may[edit | edit source]

Modic changes (MC) are bone marrow lesions seen within a vertebral body on magnetic resonance imaging (MRI), suggestive of being associated with low back pain (LBP). [1] Their presence in clients receiving physiotherapy for low back pain may be of significance when discussing prognosis and benefits of exercise therapy.

Mechanism of Injury / Pathological Process
[edit | edit source]

Research on the subject has been published since 1988 when MC were first identified by Dr. Michael Modic. Subsequent publications on the subject provided incremental gains in understanding of this new diagnostic entity. Though causes and mechanisms responsible for formation of MC are still poorly understood, progress is being made in linking his spinal phenotype with disc degeneration and LBP.

Proposed risk factors include:

  • Body mass index (BMI) ranking of overweight or obese [2][1]
  • Smoking

Clinical Presentation[edit | edit source]

add text here relating to the clinical presentation of the condition

Diagnostic Procedures[edit | edit source]

add text here relating to diagnostic tests for the condition

Outcome Measures[edit | edit source]

add links to outcome measures here (see Outcome Measures Database)

Management / Interventions
[edit | edit source]

add text here relating to management approaches to the condition

Differential Diagnosis
[edit | edit source]

add text here relating to the differential diagnosis of this condition

Resources
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add appropriate resources here

References[edit | edit source]

[1][3][2]

  1. 1.0 1.1 1.2 Mok FP, Samartzis D, Karppinen J, Fong DY, Luk KD, Cheung KM. Modic changes of the lumbar spine: prevalence, risk factors, and association with disc degeneration and low back pain in a large-scale population-based cohort. The Spine Journal. 2016 Jan 1;16(1):32-41.
  2. 2.0 2.1 Määttä JH, Wadge S, MacGregor A, Karppinen J, Williams FM. ISSLS prize winner: vertebral endplate (Modic) change is an independent risk factor for episodes of severe and disabling low back pain. Spine. 2015 Aug 1;40(15):1187-93.
  3. W Xia, C Liu, S Duan, S Xu, K Wang, Z Zhu, H Liu - PloS one, 2018