Moyamoya Disease

Original Editor - User:Wendy Walker

Top Contributors - Wendy Walker

Clinically Relevant Anatomy[edit | edit source]

Moyamoya Disease is a disorder of some of the blood vessels in the brain: the internal carotid arteries, and the arteries which branch from them. It is a rare cause of Stroke and TIAs.

2 images, both MIP reconstructed MR angiographies; one is that of an 11 year old girl with Moyamoya Disease, which shows the characteristic occluded cranial arteries, and the other image shows a healthy subject for comparison.
The image on the left: MIP reconstructed MR angiography of a 11 year old girl with Moyamoya Disease. The image on the right: a healthy subject for comparison.

It can also be referred to as Progressive Intracranial Occlusive Arteropathy, or Progressive Intracranial Arterial Occlusion.

Mechanism of Injury / Pathological Process
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The affected arteries become increasingly constricted with time, and a collateral circulation develops around the constricted arteries to compensate for the blockages. The condition is an idiopathic, non-inflammatory, non-atherosclerotic progressive vaso-occlusive disease involving the terminal supraclinoid internal carotid arteries and circle of Willis.

Clinical Presentation[edit | edit source]

The patient often presents either in childhood, aged around 5 years, or in adults in their 30s or 40s.

Diagnostic Procedures[edit | edit source]


Outcome Measures[edit | edit source]

add links to outcome measures here (see Outcome Measures Database)

Management / Interventions
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Differential Diagnosis
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Resources
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References[edit | edit source]