Neurology Medications

Original Editor - Lucinda hampton

Top Contributors - Lucinda hampton, Vidya Acharya and Rachael Lowe  

Introduction[edit | edit source]

Some of the most commonly prescribed medications by neurologists include:

Levetiracetam: a medicine used to treat epilepsy.

Gabapentin: used to treat partial seizures, nerve pain from shingles and restless leg syndrome.

Topiramate: an anticonvulsant medication used to treat epilepsy, migraine headaches, and off-label to treat various mood and eating disorders and helps in substance abuse therapy.[1]

Lamotrigine: anti-seizure/anti-epilepsy drug. Used to treat the eg. partial seizures, primary generalized tonic-clonic seizures, bipolar I disorder maintenance. Off-label uses eg. treating acute bipolar depression, fibromyalgia, schizophrenia, and unipolar depression.[2]

Carbidopa-Levodopa: used in the management and treatment of Parkinson disease (PD). Carbidopa is indicated for combination use with levodopa (L-dopa) for the treatment of motor symptoms occurring in Parkinson disease (PD) and post-encephalitic parkinsonism.[3]

Donepezil Hcl: used to treat dementia associated with mild, moderate, or severe Alzheimer's disease, and it can improve cognition and behavior, thereby alleviating certain symptoms. Donepezil Hcl is a centrally acting, rapid, reversible acetylcholinesterase inhibitor. It prevents acetylcholinesterase (an enzyme that breaks down acetylcholine) binding reversibly to acetylcholinesterase, and preventing acetylcholine hydrolysis, thereby increasing the availability of acetylcholine and enhancing nervous transmissions.[4]

Sumatriptan Succinate: used to treat migraine headaches. Used when headache symptoms first start, not used to prevent headaches.

Oxcarbazepine: used to treat epilepsy (partial siezures)

Amitriptyline Hcl: belongs to group called tricyclic antidepressants. It works on your central nervous system to increase the level of specific chemicals in your brain, which improves your depression.

Memantine Hcl: Used in Alzheimer’s disease treatment as a non-competitive modern-affinity strong voltage-dependent N-methyl-D-aspartate receptor antagonist. The therapeutic abilities of memantine are now being applied for the treatment of various psychiatric illnesses eg autism spectrum disorder, binge eating disorder, and attention-deficit/hyperactivity disorder.[5][6]

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References[edit | edit source]

  1. Very well mind Topamax (Topiramate) - Oral Available:https://www.verywellmind.com/topamax-topiramate-drug-profile-380649 (accessed 8.10.2023)
  2. Betchel NT, Fariba KA, Saadabadi A. Lamotrigine. InStatPearls [Internet] 2023 Feb 13. StatPearls Publishing.Available: https://www.ncbi.nlm.nih.gov/books/NBK470442/(accessed 8.10.2023)
  3. Leyden E, Tadi P. Carbidopa.(2020). StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2020.Available:https://www.ncbi.nlm.nih.gov/books/NBK554552/ (accessed8.10.2023)
  4. Kumar A, Gupta V, Sharma S. Donepezil. InStatPearls [Internet] 2021 Dec 22. StatPearls Publishing.Available:https://www.ncbi.nlm.nih.gov/books/NBK513257/ (accessed 8.10.2023)
  5. Lu S, Nasrallah HA. The use of memantine in neuropsychiatric disorders: An overview. Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists. 2018 Aug 1;30(3):234-48.Available:https://pubmed.ncbi.nlm.nih.gov/30028898/ (accessed 8.10.2023)
  6. Definitive Healthcare Top 10 FDA-approved drugs prescribed by neurologists Available:https://www.definitivehc.com/resources/healthcare-insights/top-fda-approved-drugs-neurologists (accessed 8.10.2023)