Original Editor - Rachael Lowe
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A wrist sprain is an injury to the ligaments of the wrist region, including the ligaments connecting the carpal bones and the ligaments connecting the proximal row of carpal bones with the radius and the ulna. By injury we mean that the ligaments are partially or completely torn. [1,4]
There are three grades: 
1. A mild overstretching of the ligaments, without joint instability.
2. A partial rupture of the ligaments, with no or mild joint instability.
3. A complete rupture of a ligament with severe joint instability.
Clinically Relevant Anatomy
There are two types of wrist sprains, namely radial and ulnar wrist sprain.
The radial wrist sprain is most common, with mostly an injury of the ligaments connecting the lunate with the scaphoid, including the scapholunate ligament and the radioscapholunate ligament. 
In case of an ulnar wrist sprain, it can be a torn of the ligaments of the triangular fibrocartilagenous complex or the luno-triquetrum complex. 
The most common mechanism of injury is a fall on an outstretched arm/hand, with an important impact on the thenar eminence, combined with a dorsiflexion, an ulnar deviation and intercarpal supination-stress. The gravity and the pattern of the injury are depending on the angle, power and the length of the impact during the fall. [2,4]
When a patient has functional disorders and pain after an acute wrist trauma, we want to know whether there is a fracture or not. In most cases they will take an X-ray to set up a diagnosis. At this moment a group of scientists is trying to set up the ‘Amsterdam Wrist Rules’, like we already know the ‘Ottawa ankle rules’. The purpose of their study is to set up guidelines that should be followed in making a decision whether you should take an X-ray of the wrist or not. 
We will start the examination with the anamnesis. During this questionnaire, we want to learn more about the origin of the injury and we can already ask if there are (according to the patient) any functional disorders. Let the patient describe the symptoms, the most frequent complaint is ‘pain’, let the patient define this pain. It will also be important to ask about the expectations of the therapy. And you can gather information about previous injuries and any possible factors that can hamper the healing process. [5,8,9]
After the anamnesis, you should do an inspection of the injured wrist, by comparing it to the other wrist. A sprained wrist can be swollen, red, tender and warm to touch. [1,5,8,9]
When you have finished the inspection, you can palpate the wrist with all her structures. Most of the structures in the wrist are very good palpable, but swelling can hinder you palpation and the palpation can be painful for the patient. [2,10]
After palpation, you should test each articulation in search of pain, abnormal motion or crepitus. The physiological movement of the wrist can be examined by simple tests of the palmar flexion, dorsiflexion, radial deviation and ulnar deviation. 
You should also test the functional movement by letting the patient do things like catching, pinching, holding and managing simple objects. 
When there is a severe swelling, you can expect that even the smallest mobilizations will be very painful for the patient. [5,9]
Next, you can do a resistance examination, to examine whether the muscle strength is still normal. You should do this for flexion (Fig.5), extension and ulnar and radial deviation. 
Beware this can be very painful or even impossible for patients with a severe wrist sprain, when the passive mobilizations are already painful and not fully practicable.
The results of your tests and thus the functional disorders will depend on the severity of the injury. [2,5,9]
You can also run some more specific provocative wrist tests [2,5,10]:
- Scaphoid Watson shift test
- fingerextensions against resistance
- Midcarpal test
- Distal radioulnar joint test
- Triangular fibrocartilage complex stress test
- Triangular fibrocartilage complex stress test with compression
- Gripping rotatory impaction test
These tests will give you more information about which ligaments are (partially) ruptured and instability of the wrist. 
If you want to learn more about the provocative tests and their relation to instability, you can consult this website: http://www.maitrise-orthop.com/corpusmaitri/orthopaedic/dumontier_synth/dumontier_us.shtml
For the evidence of the tests, refer to this article: http://www.ncbi.nlm.nih.gov/pubmed/22093123
Physical therapy management
At first, you should follow the R.I.C.E. method:
1. Rest: Stop the activity and use of the injured wrist for 48 hours or until the pain and the swelling has subsided. 
2. Ice: Apply a cold pack (wrapped in a towel) or a bag of crushed ice to the sprained wrist, for about 15 minutes, several a day for several days. Don’t ice it for more than 20 minutes at a time! 
Cryotherapy will create a superficial vasoconstriction, so that the local blood flow and haemorrhage decrease. 
There is some discussion about the effectiveness of cryotherapy, most studies approve the fact that cryotherapy has a pain-decreasing effect. There are also indications that cryotherapy would influence the inflammation, but more and bigger studies are required to prove evidence. [2,3]
3. Compression: Wrap the wrist with an elastic compression bandage and limit swelling. The bandage should push the edema fluid away from the injured tissue. Start wrapping at the base of the fingers and stop just below the elbow, so that you wrap in the direction of the heart. The wrap should be snug, but be careful not cutting off circulation. [1,7]
4. Elevate: Try to keep the wrist above heart level as often as possible, during two days. This will help drain fluid and reduce swelling around the wrist.
Nonsteroidal anti-inflammatory drugs are also recommended. [1,7]
In case of a severe wrist sprain it can be recommended to immobilize the wrist. In some rare cases a surgery may be needed to repair a ligament that was torn completely. 
In a second phase the patient should do gradual retraining exercises, including active mobilizations, to increase flexibility and range of motion, and exercises for the strengthening of the injured wrist. We have to start these exercises early in the rehabilitation, to prevent stiffness and weakness from developing and to ensure the wrist is functioning correctly. You can start exercising as soon as pain allows. It is very important that the patient is guided by the treating physiotherapist during the exercises. 
We prefer active mobilizations above the passive ones, but in some cases we can do passive mobilizations to treat hypomobility, by adding traction. 
First you can perform radiocarpal and midcarpal traction, to see whether this movement provokes pain. This handling can be used to treat hypomobility in different directions. [2,13]
To stimulate flexion you should do the dorsal sliding technique. During this technique the convex carpal bones will move in dorsal direction over the concave surface of the distal radius. [2,13]
To stimulate extension you have to do the volar sliding technique. This will cause a sliding of the convex carpal bones in the volar direction over the concave surface of the radius. [2,13]
The ulnar sliding technique will stimulate radial deviation. [2,13]
The radial sliding technique will stimulate ulnar deviation. [2,13]
After these passive mobilizations you can go to the active mobilizations. 
There are many exercises you can give to your patients, here are some examples. [2,13]
- turning the wrists: hook you fingers into each other and turn the wrist in different directions.
- Place you forearms on a table and perform extension (arm in pronation on table) and flexion (arm in supination on table).
- Do the same for ulnar and radial deviation, you can do this one in pro- and in supination.
You can combine mobilizations with some stretching exercises for the extensors and flexors. [2,13,14]
Before you start to stretch, you should perform an isometric contraction and hold this for 5 seconds. [2,13,14]
After mobilizations you can start exercises to improve muscle strength. These exercises will be very similar to the mobilizations, except from the fact that you should use some tools. By tools we mean weights, Theraband, pullmachine and many others. The goal of these tools is to put a resistance on the movement. You should start with a low resistance/weight and many repetitions to train the muscle endurance first, then gradually increase resistance/weight but decrease repetitions to train muscle strength, do this depending on the possibilities of the patient. [2,13]
It can also be useful to do some proprioceptive exercises, especially for practicing sports, like gymnastics, where the athletes frequently us the hands as weight carriers. These exercises are often performed in push-up position. You will gradually change the surface under the hands starting with flat ground, followed by, normal pillow, Airex pad, Sissel pillow and wobble board. [2,13]
It is difficult to give information about the repetitions and the durations of the exercises, because this is strongly related to the patient and his advancement. It is also important to know what the final goal of the patient will be, does he just have to return to ADL-activities or is he an athlete who has to return to his sport and on which level? You will have to consider all these things when you set up a personal training program for a specific patient. [2,13]
When returning to sport activities, the therapist can prepare the patient by taping the wrist or adjust a brace. [1,2]
add text here relating to key evidence with regards to any of the above headings
add appropriate resources here
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- Mathew Hawkes. Hawkes Physiotherapy Wrist sprain video. Available from: https://youtu.be/0AMIVnkcR0U [Accessed 2 Apr 2015]
1. Morgan WJ, Slowman LS. Acute hand and wrist injuries in athletes: Evaluation and management. Journal of the American Academy of Orthopaedic surgeons, nov.-dec. 2001, vol. 9, n°: 6, 389-400. Evidence level: 2A
2. Prof. Dr. R. Meeusen. Praktijkgids pols- en handletsels. Vrije Universiteit Brussel. Dienst uitgaven, 2006.
3. Tricia J. Hubbard; Craig R. Denegar. Does Cryotherapy Improve Outcomes With Soft Tissue Injury? Pennsylvania State University, University Park, PA. Journal of Athletic Training. Volume 39. Number 3. September 2004. Evidence level: 1A. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC522152/?tool=pubmed
4. Roald Bahr, Sverre Maehlum. Clinical Guide To Sports Injuries. 2004.
5. Christian Dumontier. Physical Examination of wrist instabilities. [INTERNET] Evidence level: 5
6. Bentohami, et al. Amsterdam wrist rules: A clinical decision aid. BMC Musculoskeletal Disorders. 17 october 2011. Evidence level: 1B Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229467/?tool=pubmed
7. Wolfe MW, Uhl TL, Mattacola CG, McCluskey LC. Management of ankle sprains. Erratum in Am Fam Physician 2001 Aug1;64(3):386. Evidence level: 2C
8. Peter Vaes, Eric Kerckhofs, David Beckwée. Het Gezondheidsprofiel. Standaard uitgeverij.
9. Honing, E. Wrist injuries – pinpointing pathology in a complex joint. Phys sportsmed, 26(9): 41-49, 1998a. Evidence level: 5
10. Prosser R, Harvey L, Lastayo P, Hargreaves I, Scougall P, Herbert RD. Provocative wrist tests and MRI are of limited diagnostic value for suspected wrist ligament injuries: a cross-sectional study. Australian Physiotherapy Association. Evidence level: 1B
11. Rettig, A. Elbow, forearm and wrist injuries in athlete. Sports Med, 25(2):115-130, 1998. Evidence level: 2C
12. Levine W. Rehabilitation techniques for ligament injuries of the wrist. Hand Clin 8(4):669-681, 1992. Evidence level: 5
13. Wadsworth C. The wrist and hand. In: Malone T., McPoil T., Nitz A.. Orthopedic and sports physical therapy. Mosby, St. Louis, USA.pp. 327-378,1997
14. Humphrey D. Flexibility for the wrist, fingers and thumbs. Phys Sportsmed, 18(12):147-148, 1990. Evidence level: 5