Myalgic Encephalomyelitis or Chronic Fatigue Syndrome: Difference between revisions
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== Differential Diagnosis == | == Differential Diagnosis == | ||
The following are possible differential diagnoses<ref name="Goodman">Goodman CC., Fuller KS. Pathology: implications for the physical therapist. 3rd ed. St. Louis: Saunders; 2009.</ref>: | |||
*Fibromyalgia | |||
*Patients usually demonstrate with increased pain, while patients with CFS experience greater fatigue. Some consider CFS and fibromyalgia to be one in the same; others believe CFS is an early form of fibromyalgia. | |||
*Mononucleosis | |||
*Lyme Disease | |||
*Thyroid conditions | |||
*Diabetes | |||
*MS | |||
*Various Cancers | |||
*Depression | |||
*Bipolar disorder | |||
*Myalgic encephalomyelitis<ref name="White">White PD, Goldsmith KA, Johnson AL, et al. Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomized trial. Lancet. 2011;377:823-836.</ref><br> | |||
== Case Reports/ Case Studies == | == Case Reports/ Case Studies == |
Revision as of 05:38, 1 April 2012
Original Editors - Sarah Carlisle & Jill Thompson from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
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Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
While studies have investigated the use of various medications, none have been found to have consistent results. However, the following drugs are used to address and manage symptoms[1]:
- Medications to reduce pain, discomfort, and fever
- Medications to treat anxiety
- Medications to treat sleep disturbance (amitryptyline, nefazodone[2])
- Medications to treat joint pain (amytryptyline[2])
- Medications to treat depression (sertralin, paroxetine, nefazodone[2])
- Anti-inflammatory drugs (aspirin, acetaminophen[2])
- NSAIDS to address headache relief[2]
- Deydroepiandrosterone (DHEA) was found in a pilot study to significantly reduce the pain, helplessness, anxiety, thinking, memory, and activities of daily living difficulties associated with CFS; however, further research is necessary[2].
- Based on current evidence corticosteroids cannot be recommended for CFS due to complications of long-term use, Mineralcorticoids and Intravenous Immunoglobulin are not recommended either and need further research[2][3]
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
The following are possible differential diagnoses[4]:
- Fibromyalgia
- Patients usually demonstrate with increased pain, while patients with CFS experience greater fatigue. Some consider CFS and fibromyalgia to be one in the same; others believe CFS is an early form of fibromyalgia.
- Mononucleosis
- Lyme Disease
- Thyroid conditions
- Diabetes
- MS
- Various Cancers
- Depression
- Bipolar disorder
- Myalgic encephalomyelitis[5]
Case Reports/ Case Studies[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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- ↑ Teitel AD MD MBA, Zieve D MD MHA. Chronic fatigue syndrome. PubMed Health: A.D.A.M. Medical Encyclopedia. 2012. Available from: PubMed.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gur, A., Oktayoglu, P. Central nervous system abnormalities in fibromyalgia and chronic fatigue syndrome: new concepts in treatment. Current Pharmaceutical Design. 2008: 14;1274-1294. Available from: PubMed.
- ↑ Vinjamury, S.P. MD, Singh, B.S. PhD. Ayurvedic Treatment of chronic fatigue syndrome-a case report. Alternative Therapies in Health and Medicine. Sept/Oct 2005: 11(5);76-78. Available from: PubMed.
- ↑ Goodman CC., Fuller KS. Pathology: implications for the physical therapist. 3rd ed. St. Louis: Saunders; 2009.
- ↑ White PD, Goldsmith KA, Johnson AL, et al. Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomized trial. Lancet. 2011;377:823-836.