Liver Function Tests: Difference between revisions

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== Introduction ==
== Introduction ==
Groups of blood tests performed to know the condition of a liver of a patient are known as Liver function tests (LFT) or liver panel or hepatic function panel or hepatic panel.<ref>Teshome G, Ambachew S, Fasil A, Abebe M. [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803769/ Prevalence of liver function test abnormality and associated factors in type 2 diabetes mellitus: a comparative cross-sectional study]. Ejifcc. 2019 Oct;30(3):303.</ref>


== Sub Heading 2 ==
== Components of Liver Function Tests ==
 
=== Alanine Transaminase ===
'''Normal Value:''' 0–45 IU/l.
 
=== Aspartate Transaminase ===
'''Normal Value:''' 0–35 IU/l.
 
'''Clinical Significance:'''
{| class="wikitable"
!Causes of Raised Transaminases
|-
|
* Alcohol.
* Medications: non-steroidal anti-inflammatory drugs, antibiotics, HMG Co-A-reductase inhibitors, antiepileptic drugs, antituberculous drugs, herbal medications, illicit drug use.
* Non-alcoholic steatohepatosis.
* Chronic hepatitis B and C.
* Autoimmune diseases.
* Hemochromatosis.
* Wilson's disease.
* Congestive cardiac failure and ischaemic hepatitis.
* ɑ<sub>1-</sub>Antitrypsin deficiency.
* Coeliac disease.
* Endocrine disease: hypothyroidism, Addison's disease.
* Diseases of striate muscle.
* Glycogen storage diseases.
|}


== Sub Heading 3 ==
== Sub Heading 3 ==

Revision as of 08:14, 29 November 2020

Original Editor - User Name

Top Contributors - Shwe Shwe U Marma, Lucinda hampton and Kim Jackson  

Introduction[edit | edit source]

Groups of blood tests performed to know the condition of a liver of a patient are known as Liver function tests (LFT) or liver panel or hepatic function panel or hepatic panel.[1]

Components of Liver Function Tests[edit | edit source]

Alanine Transaminase[edit | edit source]

Normal Value: 0–45 IU/l.

Aspartate Transaminase[edit | edit source]

Normal Value: 0–35 IU/l.

Clinical Significance:

Causes of Raised Transaminases
  • Alcohol.
  • Medications: non-steroidal anti-inflammatory drugs, antibiotics, HMG Co-A-reductase inhibitors, antiepileptic drugs, antituberculous drugs, herbal medications, illicit drug use.
  • Non-alcoholic steatohepatosis.
  • Chronic hepatitis B and C.
  • Autoimmune diseases.
  • Hemochromatosis.
  • Wilson's disease.
  • Congestive cardiac failure and ischaemic hepatitis.
  • ɑ1-Antitrypsin deficiency.
  • Coeliac disease.
  • Endocrine disease: hypothyroidism, Addison's disease.
  • Diseases of striate muscle.
  • Glycogen storage diseases.

Sub Heading 3[edit | edit source]

Resources[edit | edit source]

  • bulleted list
  • x

or

  1. numbered list
  2. x

References[edit | edit source]