Kawasaki Disease: Difference between revisions
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== Definition/Description == | == Definition/Description == | ||
Kawasaki disease, also known as mucocutaneous lymph node syndrome (pathology), is a medium-sized vessel vasculitis that affects children, especially of Japanese descent, usually between the ages of 1 and 8. In 20% of untreated patient, the coronary arteries can be affected by the vasculitis. The cardiac involvement can cause acute myocarditis with heart failure, arrhythmias, pericarditis, endocarditis, and sometimes coronary artery aneurysms. Acquired heart disease in children is predominantly cause by this disease. Other areas of the body affected by the inflammation are the kidneys, biliary tract, upper respiratory tract, and pancreas. Only 2% of patients will have a reoccurrence, which will usually occur months to years later. (Merck Manual) | |||
The prognosis is generally good for patient’s who are able to get treatment early enough, although there is the possibility of serious cardiovascular problems developing later on in life. For those who develop a large aneurysm (larger diameter than 8 mm) have the worst prognosis, as those will probably not regress or resolve. In some patients, severe ischemic heart disease can arise, which may necessitate a heart transplant. (pathology)<br><br> | |||
== Prevalence == | == Prevalence == | ||
Revision as of 19:49, 3 April 2011
Original Editors - Megan Castagno from Bellarmine University's Pathophysiology of Complex Patient Problems project.
Lead Editors - Your name will be added here if you are a lead editor on this page. Read more.
Definition/Description[edit | edit source]
Kawasaki disease, also known as mucocutaneous lymph node syndrome (pathology), is a medium-sized vessel vasculitis that affects children, especially of Japanese descent, usually between the ages of 1 and 8. In 20% of untreated patient, the coronary arteries can be affected by the vasculitis. The cardiac involvement can cause acute myocarditis with heart failure, arrhythmias, pericarditis, endocarditis, and sometimes coronary artery aneurysms. Acquired heart disease in children is predominantly cause by this disease. Other areas of the body affected by the inflammation are the kidneys, biliary tract, upper respiratory tract, and pancreas. Only 2% of patients will have a reoccurrence, which will usually occur months to years later. (Merck Manual)
The prognosis is generally good for patient’s who are able to get treatment early enough, although there is the possibility of serious cardiovascular problems developing later on in life. For those who develop a large aneurysm (larger diameter than 8 mm) have the worst prognosis, as those will probably not regress or resolve. In some patients, severe ischemic heart disease can arise, which may necessitate a heart transplant. (pathology)
Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
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