Psoriatic Arthritis
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
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Prevalence[edit | edit source]
- Occurs in 20% of persons that have psoriasis [1]
- 1%-3% of general population has psoriasis [2]
- Equal prevalence in both males and females [1]
- Can occur at any age but typically occurs between ages of 20-30 years old [2]
Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities
- Psoriasis
- Presence of HLA-B27
Medications[edit | edit source]
- NSAIDS
- Local Corticosteroid Injections
Aggressive Cases
- DMARD Therapy with MTX, SSZ, and TNF-Beta Antagonists [1]
Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
- X-rays are often performed to detect bone erosion
- Blood work will be done to detect for the HLA-B27 since it is a common histocompatibility complex marker in people with psoriatic arthritis.
- A blood test for rheumatoid factor should be done to rule out rheumatoid arthritis
Causes[edit | edit source]
Psoriatic arthritis seems to have a genetic cause although the exact marker genes have not been identified. Having a first-degree realtive with psoriatic arthritis increases the likihood of contracting the disease by 80-90%.[1]
Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
- Osteoarthritis
- Rheumatoid Arthritis
- Gaut
- Mallet finger due to traumatic injury
Case Reports[edit | edit source]
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Recent Related Research (from Pubmed)[edit | edit source]
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[1]References [2][edit | edit source]
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- ↑ Menter A, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis. Section 5. Guidelines of care for the treament of psoriasis with phototherapy and photochemotherapy. Journal of the American Academy of Dermatology. 2010;62(1):114-135.