Methamphetamine Abuse
Original Editors - Seth Pinkerton & Jessica Sparks from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
Methamphetamine is a central nervous system stimulant similar to the drug amphetamine and is classified as a Schedule II drug due to its high potential for abuse. It affects the brain by increasing the release and blocking the reuptake of dopamine which is a common mechanism of action for most drugs that are abused.
Dopamine is a neurotransmitter responsible for the reward, motivation, and pleasure centers of the brain. Methamphetamine causes a rapid release of dopamine in the brain resulting in an intense euphoric or grandeur feeling which is what leads many people to become addicted.[1]
Methamphetamine is a white, odorless, bitter tasting crystalline powder which can easily be dissolved in water or other liquids. It is taken orally, intranasally (snorting), by smoking, or intravenously.
Meth can be made from common household substances including:
Pseudoephedrine - decongestant
iodine crystals
battery acid
red phosphorus – match boxes and road flares
anhydrous ammonia – fertilizer or countertop cleaner
toluene – brake fluid
hydrochloric acid
acetone – nail polish remover or paint thinner
sodium hydroxide - lye
sulfuric acid – drain or toilet bowl cleaner[2]
Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
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Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
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Etiology/Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
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Case Reports/ Case Studies[edit | edit source]
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Resources
[edit | edit source]
Visit this website to find publicly funded treatment facilities in USA by state www.findtreatment.samhsa.gov
Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
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- ↑ National Institute on Drug Abuse. http://www.drugabuse.gov/publications/infofacts/methamphetamine. (accessed 25 March 2012)
- ↑ Meth Project. What's in Meth. http://www.methproject.org/answers/whats-meth-made-of.html?gclid=CI3C--m7j68CFYMKKgodIkCUyQ#Whats-in-Meth (accessed 25 March 2012)