Frontal Lobe Brain Injury

Original Editor - Wendy Walker

Lead Editors - Wendy Walker, Lucinda hampton, Aminat Abolade, Kim Jackson, Claire Knott and WikiSysop

Introduction

The frontal lobe is a relatively large lobe of the brain, extending from the front of the brain almost halfway towards the back of the brain. Damage to the frontal lobe of the brain can cause a range of symptoms, including motor weakness and behavioral problems. A variety of conditions can damage the frontal lobe, including stroke, head trauma, and dementia.

Symptoms of damage to the frontal lobe can vary because of the many functions carried out by the frontal lobes. Symptoms may include one or more of the following:

• Weakness on one side of the body or one side of the face
• Falling
• Inability to problem solve or organize tasks
• Reduced creativity
• Impaired judgment
• Reduced sense of taste or smell
• Depression
• Changes in behavior
• Low motivation
• Low attention span, easily distracted1
• Reduced or increased sexual interest or peculiar sexual habits
• Impulsive or risky behavior

Anatomy

In evolutionary terms the frontal cortex has been the most recent to evolve, and the frontal lobes are the area of brain which has developed greatly in humans, differentiating us from other mammals. These lobes integrate the other brain areas, and are particularly responsible for higher level thinking and cognitive skills such as planning, evaluating likely outcomes, multitasking, performing risk assessment and the niceties of social interaction; it is the area of brain which deals in abstract concepts.

The Frontal Lobes account for approximately one third of human brain mass. They lie at the front of the brain, anterior to the parietal lobes and superior to the temporal lobe. Each frontal lobe (left and right) is generally considered to have several distinct divisions:

• Motor cortex
• Premotor cortex
• Supplementary motor cortex
• Prefrontal cortex
• Orbital cortex AKA frontal eye fields
• Broca's Area

Vascular Supply: Medial frontal lobe: anterior cerebral artery and Deep & lateral regions: superior division of middle cerebral artery

Function

The frontal lobe modifies and imposes constraints on reflexive behaviours, and this control develops as the infant brain grows and the frontal lobes become larger and more active.

• Motor cortex: voluntary movement
• Premotor cortex: storage of motor programs, sensorimotor integration, facilitation of controlled, smooth movements
• Prefrontal cortex: ability to concentrate; inhibition of reflexive behaviours; personality & emotional traits; abstract thinking. Working memory, executive functions including the ability to plan & implement (& monitor/evaluate) a series of goal-directed actions.
• Broca's Area: Motor control of speech  
• Supplementary Motor Cortex: Intentional preparation for movement, procedural memory
• Frontal Eye Fields: Control of voluntary scanning movements of the eye

Damage - Causes

A variety of factors can lead to damage of your frontal lobe, such as:

• head injury (It has been found that in traumatic brain injury contusions typically occur on the poles and the inferior aspects of the frontal lobes.)
• stroke
• infection that affects the frontal lobe
• tumors in the frontal lobe
• multiple sclerosis
• neurodegenerative diseases eg Alzheimer’s disease Parkinson’s disease Huntington’s disease

Treatment and Rehabilitation.

Treatment for damage to the frontal lobe depends on the cause. Frontal lobe damage treatment plans include a team of several types of healthcare professionals.

Some examples of potential treatments for frontal lobe damage include:

• Physical therapy to help maintain or regain mobility, strength, and flexibility.
• Occupational therapy to help learn new strategies to perform daily tasks and activities eg getting dressed, eating, or bathing.
• Vocational counseling.
• Speech-language therapy to aid in improving communication or teaching how to use assistive devices.
• Cognitive therapy, working on skills like planning, judgment, and memory.
• Psychological therapy to help improve relationships, emotional responses, and coping skills.
• Surgery. Surgery may be recommended in cases when an injury or brain tumor is causing damage.
• In some cases, the cause of the frontal lobe damage may be permanent. eg neurodegenerative diseases. In these cases, treatment may also involve medications.

3 Frontal Lobe Syndromes

1. Orbitofrontal syndrome Lack of Inhibition. Patient demonstrates disinhibited, impulsive behaviour; difficulty in controlling their emotions; difficulty in maintaining concentration; lacking in judgement; failure to appreciate/anticipate consequences of their actions; can show euphoria, hypomania or grandiosity. Can also lead to abnormal sexual behaviour.
2. Frontal convexity syndrome Apathetic. Patient shows disinterest and is apathetic; slowing of motor functions; unable to plan ahead; lacks motivation; lacks concern about the world around them.  
3. Medial frontal syndrome Akinetic. Reduced movement; loss of sensation in lower limbs; urinary incontinence; occasional mutism; profound apathy; sometimes show indifference to thirst or hunger

References

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