Sarcoidosis

 

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Original Editors - Jordan Bormann from Bellarmine University's Pathophysiology of Complex Patient Problems project.

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Sarcoidosis (sar-coy-doe-sis) is a potentially life threatening disease with no known cause or cure. The duration of this disease varies and can last from only a few short months to several years. Often times, sarcoidosis is self-limiting needing no medicinal treatment. The primary manifestation of sarcoidosis includes inflammation of the lungs as well as many other bodily organs. About 90% of diagnosed cases are deemed to be pulmonary sarcoidosis. The pulmonary involvement affects the lungs by forming inflamed masses of tissue known as granulomas in the lung parenchyma (alveoli, bronchioles) and lymph nodes^1,2. Results include stiffness of the lungs due to scar tissue formation causing decreased oxygen uptake and gas exchange in the bloodstream². Other involvement of sarcoidosis can manifest itself as inflammation of the epithelial tissue, eyes, liver, spleen, heart, kidneys, central nervous system (CNS) and bones of the hands or feet¹. Although this disease has not always been well known, cases have been recorded worldwide and are becoming increasingly more common³.

Prevalence

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Characteristics/Clinical Presentation

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Associated Co-morbidities

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Medications

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Diagnostic Tests/Lab Tests/Lab Values

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Etiology/Causes

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Systemic Involvement

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Medical Management (current best evidence)

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Physical Therapy Management (current best evidence)

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Alternative/Holistic Management (current best evidence)

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Differential Diagnosis

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Case Reports/ Case Studies

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Resources

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Recent Related Research (from Pubmed)

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References

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