Leicester Cough Questionnaire
Leicester Cough Questionnaire (LCQ) is an English-born self-reporting quality of life measure of chronic cough, developed by S.S. Birring. It consists of 19 items with a 7 point Likert response scale (range from 1 to 7), a format example is available here. Each item is developed to assess symptoms during cough and impact of cough on three main domanins: physical, psychological andsocial. Scores are calculated as mean of each domain and total score is calculated by adding every domanin score. It generally takes about 5 minutes to be completed and it is designed for adults. Since the first development in 2003 LCQ has been translated and validated in several languages (Dutch, French, Korean, Lithuanian, Mandarin Chinese, Polish, Portuguese, Spanish, Swedish, Thai). LCQ has been used as an outcome measure for different respiratory diseases like COPD, Cystic Fibrosis, non-CF bronchiectasis.
This instrument has been developed to detect the effect of chronic cough on health status and consequently on quality of life of chronic respiratory diseases patients.
Clinimetric properties of LCQ
Concurrent validity measures how much a test correlates well with another measure that has previously been validated.
|Concurrent Validity||English Vers.||Dutch Vers.||Mandarin Vers.||Korean Vers.||French Vers.||Thai Vers.||Spanish Vers.||Swedish Vers.||Polish Vers.||Lithuanian Vers.|
|SGRQ - total||-0.56||-0.60||-0.66||-0.55||-0.49|
|SF36 – total||0.46||0.41||0.55||0.33|
|Borg Cough Scale||-0.41||-0.74|
|HADS - total||-0.46||-0.36||u.v.|
|Cough symptom score||-0.66|
SGRQ: Saint George respiratory Questionnaire; VAS: Visual Analogue Scale; SF-36: Short Form-36; HADS: Hospital Anxiety and Depression Scale; CASA-Q: Cough and Sputum Assessment Questionnaire; CAT: COPD Assessment Test; EQ5D: EuroQol five-dimensional Questionnaire; u.v.: unreported value by authors because non significant
All data are expressed as r-correlation coefficient between total scores of each instruments listed and are all statistically significant unless specified.
Repeatability or test–retest reliability reflects the agreement between the results of successive measurements of the same "test" or "instrument" that occurs under the same conditions of the previous measurement
|Repeatability||Intraclass Correlation Coefficient|
|Mandarin Chinese Version||0.89|
|Internal consistency and Reliability||Cronbach’s
|Mandarin Chinese Version||0.93|
- Birring, S. S., et al. "Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ)." Thorax 58.4 (2003): 339-343.
- Huisman, Arnold N., et al. "Reliability and validity of a Dutch version of the Leicester Cough Questionnaire." Cough 3.1 (2007): 3.
- Reychler, Gregory, et al. "Validation of the French version of the Leicester Cough Questionnaire in chronic obstructive pulmonary disease." Chronic respiratory disease 12.4 (2015): 313-319.
- Kwon, Jae-Woo, et al. "Reliability and validity of a Korean version of the leicester cough questionnaire." Allergy, asthma & immunology research 7.3 (2015): 230-233.
- Merkytė, I., et al. "Reliability and Validity of a Lithuanian version of Leicester Cough Questionnaire." J Lung Pulm Respir Res 3.5 (2016): 00099.
- Gao, Y. H., et al. "Validation of the Mandarin Chinese version of the Leicester Cough Questionnaire in bronchiectasis." The International Journal of Tuberculosis and Lung Disease 18.12 (2014): 1431-1437.
- Maskey-Warzęchowska, Marta, and Piotr Korczyński. "Validation of the Polish Version of the Chronic Cough Quality of Life Questionnaire (Leicester Cough Questionnaire)." (2016).
- Felisbino, Manuela Brisot, et al. "Leicester Cough Questionnaire: translation to Portuguese and cross-cultural adaptation for use in Brazil." Jornal Brasileiro de Pneumologia 40.3 (2014): 213-221.
- Muñoz, Gerard, et al. "Validation of a Spanish version of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis." Chronic respiratory disease 13.2 (2016): 128-136.
- Sönnerfors, Pernilla, Gun Faager, and Ulrika Einarsson. "Translation of the Leicester Cough Questionnaire into Swedish, and validity and reliability in chronic obstructive pulmonary disease." Disability and rehabilitation (2017): 1-9.
- Pornsuriyasak, Prapaporn, et al. "Validity and reliability of the Thai version of the leicester cough questionnaire in chronic cough." Asian Pacific journal of allergy and immunology 34.3 (2016).
- Berkhof, Farida F., et al. "The validity and precision of the Leicester Cough Questionnaire in COPD patients with chronic cough." Health and quality of life outcomes 10.1 (2012): 4.
- Ward, Nathan, et al. "The psychometric properties of the Leicester Cough Questionnaire and Respiratory Symptoms in CF tool in cystic fibrosis: A preliminary study." Journal of Cystic Fibrosis 16.3 (2017): 425-432.
- Murray, M. P., et al. "Validation of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis." European Respiratory Journal 34.1 (2009): 125-131.