Spondyloarthropathy--AS: Difference between revisions
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== Clinically Relevant Anatomy == | == Clinically Relevant Anatomy == | ||
The vertebral column exists of 24 vertebrae: seven [[Cervical_Vertebrae|cervical vertebrae]], twelve thoracic vertebrae and five [[Lumbar_Vertebrae|lumbar vertebrae]]. The vertebrae are joined together by ligaments and separated by intervertebral discs. The discs exist of an inner nucleus pulposus and an outer annulus fibrosis, consisting of fibrocartilage rings.<br>Patients with spondyloarthropathy have a high propensity for inflammation at the sites where tendons, ligaments and joint capsules attach to the bone. These sites are known as entheses. <ref name="23">Benjamin M. and McGonagle D., The anatomical basis for disease localization in seronegative spondyloarthropathy at entheses and related sites. J. Anat., 2001. Level of Evidence 5</ref>Level 5<br> | |||
The[[Sacroiliac_joint|sacroiliac joint]] consists of a cartilaginous part and a fibrous (or ligamentous) compartment with very strong anterior and posterior sacroiliac ligaments. This makes the SIJ an amphiarthrosis with movement restricted to slight rotation and translation. Another specific feature of the SIJs is that two different types of cartilage cover the two articular surfaces. While the sacral cartilage is purely hyaline, the iliac side is covered by a mixture of hyaline and fibrous cartilage. Due to its fibrocartilaginous components, the sacroiliac joint is a so-called articular enthesis.<ref name="24">Hermann K.G.A., Bollow M., Magnetic Resonance Imaging of Sacroiliitis in Patients with Spondyloarthritis: Correlation with Anatomy and Histology. Fortschr Röntgenstr, 2014, 186:3, 230-237 Level of Evidence 1B</ref>Level 1B | |||
== Epidemiology /Etiology == | == Epidemiology /Etiology == |
Revision as of 18:49, 1 February 2017
Original Editors
Top Contributors - Adam Bockey, Elise Jespers, Elaine Lonnemann, Kim Jackson, Admin, 127.0.0.1, WikiSysop, Wendy Walker and Lucinda hampton
Search Strategy[edit | edit source]
Keywords: spondyloartrhropathy, ankylosing spondylitis, Reiter's syndrome, Marie-Strumpell disease, bamboo spine
Databases: PubMed, Pedro, Web of Science, emedicine
Definition/Description[edit | edit source]
Spondyloarthropathies are a diverse group of inflammatory arthritides that share certain genetic predisposing factors and clinical features. The group primarily includes Ankylosing Spondylitis, reactive arthritis (including Reiter’s syndrome), psoriatic arthritis, inflammatory bowel disease–associated spondyloarthropathy, and undifferentiated spondyloarthropathy.Cite error: Invalid <ref>
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The primary pathologic sites are the sacroiliac joints, the bony insertions of the annulus fibrosis of the intervertebral discs, and the apophyseal joints of the spine.Cite error: Invalid <ref>
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Ankylosing Spondylitis (AS) also known as Marie- Strumpell disease or bamboo spine, is an inflammatory arthropathy of the axial skeleton, usually involving the sacroiliac joints, apophyseal joints, costovertebral joints, and intervertebral disc articulations.Cite error: Invalid <ref>
tag; name cannot be a simple integer. Use a descriptive title AS is a chronic progressing inflammatory disease that causes inflammation of the spinal joints that can lead to severe, chronic pain and discomfort. In advanced stages, the inflammation can lead to new bone formation of the spine, causing the spine to fuse in a fixed position often creating a forward stooped posture.Cite error: Invalid <ref>
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Clinically Relevant Anatomy[edit | edit source]
The vertebral column exists of 24 vertebrae: seven cervical vertebrae, twelve thoracic vertebrae and five lumbar vertebrae. The vertebrae are joined together by ligaments and separated by intervertebral discs. The discs exist of an inner nucleus pulposus and an outer annulus fibrosis, consisting of fibrocartilage rings.
Patients with spondyloarthropathy have a high propensity for inflammation at the sites where tendons, ligaments and joint capsules attach to the bone. These sites are known as entheses. Cite error: Invalid <ref>
tag; name cannot be a simple integer. Use a descriptive titleLevel 5
Thesacroiliac joint consists of a cartilaginous part and a fibrous (or ligamentous) compartment with very strong anterior and posterior sacroiliac ligaments. This makes the SIJ an amphiarthrosis with movement restricted to slight rotation and translation. Another specific feature of the SIJs is that two different types of cartilage cover the two articular surfaces. While the sacral cartilage is purely hyaline, the iliac side is covered by a mixture of hyaline and fibrous cartilage. Due to its fibrocartilaginous components, the sacroiliac joint is a so-called articular enthesis.Cite error: Invalid <ref>
tag; name cannot be a simple integer. Use a descriptive titleLevel 1B
Epidemiology /Etiology[edit | edit source]
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