Dyspnoea

Original Editor -Safiya NazTop Contributors - Safiya Naz, Kim Jackson and Lucinda hampton

Introduction

Dyspnoea (also is known as dyspnea, shortness of breath or breathlessness).

• The sensation of uneasy breathing and indicates a medical emergency,
• Dyspnoea represents one of the most frequent cardinal symptoms globaly
• It is a sensation of lacking of the air and of not being able to breathe normally
• "Is a subjective sensation which probably develops as a result of the integration of signals from the central nervous system and some peripheral receptors."

Mechanism

• Dyspnoea starts from the unfit response of the respiratory system to the uninhibited motor control.
• "The sensation of dyspnoea seems to originate with the activation of sensory systems involved in respiration. Sensory information is, in turn, relayed to higher brain centers where central processing of respiratory-related signals and contextual, cognitive and behavioral influences shape the ultimate expression of the evoked sensation. The homeostatic systems involved in the regulation of respiration provide a framework for understanding the mechanisms of dyspnea

The neural basis of dyspnea is likely to involve activation of both the cortex and the limbic system"

• Dyspnoea is a heightened level of awareness of respiratory sensation and has a strong emotional component.
• Healthy subjects can experience Dyspnoea in different situations, e.g. at high altitude, after breath-holding, during stressful situations that cause anxiety or panic, and more commonly during strenuous exercise.
• Many factors play an important role in the mechanisms of dyspnea: functional status or respiratory muscles, mechanical and chemical afferents, central motor output.
  

Types

1. Orthopnea - it is the sensation of dyspnoea in the recumbent position, relieved by sitting or standing.
2. Paroxysmal nocturnal dyspnea (PND) - it is a sensation of dyspnoea that awakens the patient, often after 1 or 2 hours of sleep, and is usually relieved in the upright position.
3. Trepopnea - it is a sensation of dyspnoea that occurs in one lateral decubitus position as opposed to the other.
4. Platypnea - it is a sensation of dyspnoea that occurs in the upright position and is relieved with recumbency.

Clinical Presentation

Some characteristics of a sensation of Dyspnoea with different disorders; these are guidelines only, and patients vary Disorder.

COPD Asthma Interstitial lung disease Pneumonia Pneumothorax Hyperventilation Pulmonary oedema Neuromuscular Deconditioning Obesity/pregnancy

Slow onset Episodic, on exhalation Progressive, exertional Exertional Moderate/severe Air hunger, not relieved by rest Positional, on inhalation Exertional, on inhalation Heavy Exertional

Diagnostic Procedures

History Examination

The history and physical exam should ascertain whether there are any ongoing cardiovascular, pulmonary, musculoskeletal, or psychiatric illnesses. Key components of the history to collect include onset, duration, and occurrence with rest or exertion.

• "A patient with dyspnoea may say: "I feel short of breath," "I'm having difficulty breathing," "I can't catch my breath," "I feel like I'm suffocating." Because it is a subjective phenomenon,
• The perception of dyspnoea and its interpretation vary from patient to patient. Begin with a nonleading question:
• Do you have any difficulty breathing? If the response is affirmative and dyspnoea is established as a problem, it should be characterized in detail. When did it begin? Has the onset been sudden or insidious? Inquire about the frequency and duration of attacks.
• The conditions in which dyspnoea occurs should be ascertained. Response to activity, emotional state, and change of body position should be noted. Ask about associated symptoms: chest pain, palpitations, wheezing or coughing. Sometimes a nonproductive cough may be present as a " dyspnoea equivalent." What other significant medical problems does the patient have, and what medications has he been taking? How much has he smoked?
• Additional questions should be aimed at ascertaining whether the patient has orthopnea or paroxysmal nocturnal dyspnoea.
• Inquire about the number of pillows he uses under his head at night and whether he has ever had to sleep sitting up. Does he develop coughing or wheezing in the recumbent position? Did he ever wake up at night with shortness of breath? How long after lying down did the episode occur, and what did he do to relieve his distress?
• Characteristically, the patient with left ventricular failure sits up at bedside, dangles his feet, and refrains from ambulation or other activity that is likely to worsen his symptoms"

Physical Examination

• "Physical exam should begin with a rapid assessment of the ABCs (airway, breathing, and circulation).
• Once a patient is determined to be stable, a full physical exam can be done.
• To determine the severity of dyspnoea, observe respiratory effort, use of accessory muscles, mental status, and speaking ability.
• Distention of the neck veins implies cor pulmonale caused by severe COPD, congestive heart failure, or cardiac tamponade.
• Thyromegaly may indicate hyperthyroidism or Hypothyroidism. The tracheal deviation may indicate possible anatomic abnormality or pneumothorax.
• Auscultate for stridor in the upper airways indicates obstructed airway. Palpation of the chest can determine the presence of subcutaneous emphysema or crepitus. Percussion of the lung lobes for dullness can determine the presence or absence of consolidation and effusion.
• Hyperresonance on percussion is a worrisome finding that indicates possible pneumothorax or severe bullous Emphysema.
• Lung Auscultation may reveal absent breath sounds indicating the presence of pneumothorax or region occupying mass such as pleural effusion or malignancy.
• The presence of wheezing is highly consistent with the diagnosis of obstructive lung diseases such as asthma or COPD.  However, wheezing may be associated with pulmonary oedema or pulmonary embolism. Pulmonary oedema and pneumonia may present with rales on auscultation.
• Auscultation of the heart may reveal the presence of dysrhythmia, cardiac murmurs, or aberrant heart gallops. An S3 gallop indicates cardiac overfilling seen in left ventricular systolic dysfunction and congestive heart failure. An S4 gallop suggests left ventricular dysmotility and dysfunction. A loud P2 indicates possible pulmonary hypertension. Murmurs may indicate valvular dysfunction. Diminished heart sounds may indicate cardiac tamponade.
• Pericarditis may present with a rubbing cardiac sound on auscultation. On abdominal examination, hepatomegaly, ascites, positive hepatojugular reflux may indicate the diagnosis of congestive heart failure.
• Lower extremities oedema is associated with congestive heart failure, and extreme swelling of the extremities suggest possible deep venous thrombosis that can lead to a pulmonary embolism. Digits clubbing is present in some forms of lung malignancy or severe chronic hypoxia. Cyanosis of the extremities indicates hypoxia".
  

Differential Diagnosis

• Dyspnoea is a cardinal symptom. it has arisen from four primary categories: respiratory, cardiac, neuromuscular, psychogenic, systemic illness, or a combination of these.
• Asthma, acute exacerbation of or chronic congestive obstructive pulmonary disorder (COPD), pneumonia, pulmonary Embolism, lung malignancy, pneumothorax, or aspiration comes under respiratory.
• Congestive heart failure, pulmonary oedema, acute coronary syndrome, pericardial tamponade, valvular heart defect, pulmonary hypertension, cardiac arrhythmia, or intracardiac shunting indicates cardiovascular
• Chest trauma with fracture or flail chest, massive Obesity, kyphoscoliosis, central nervous system (CNS) or spinal cord dysfunction, phrenic nerve paralysis, myopathy, and neuropathy shows neuromuscular
• Psychogenic causes may include hyperventilation syndrome, psychogenic dyspnea, vocal cord dysfunction syndrome, and foreign body aspiration.
• Systemic illnesses may include anaemia, acute renal failure, metabolic acidosis, thyrotoxicosis, cirrhosis of the liver, anaphylaxis, sepsis, angioedema, and epiglottitis

Physiotherapy Management

• Dyspnoea both acute or chronic with acute occurring under 3 weeks and chronic more than 4 up to 8 weeks.
• "Acute dyspnoea typically is due to a more life-threatening process and requires rapid intervention.
• All patients should be placed on supplemental oxygen, pulse oximetry, and a cardiac monitor.."
• Aerobic
• walking
• Cycling
• Diaphragmatic breathing
• Resistance exercise training
• Many dyspnoeic people find self posture which eases their breathing,
• Patients with a flat diaphragm may benefit from positions that use pressure from the abdominal contents to dome the muscle.
• The arms are best supported, to optimize accessory muscle function, but without tension or active fixation
• Pursed Lip Breathing relieve dyspnoea and increasing exercise tolerance, sustained improvement in exertional dyspnoea and physical function
• Evidence from this review indicates that some form of upper limb exercise training when compared to no upper limb training or a sham intervention improves dyspnoea
• Positions to facilitate efficient breathing in dyspnoeic people include:

1. "High side-lying.
2. Sitting upright in a chair with supporting arms; for many patients, it is easier to breathe in this position than in bed. Some like to lean back for support, others prefer to lean slightly forward to put some stretch on the diaphragm
3. Sitting leaning forward from the waist, arms resting on pillows on a table, feet on the floor
4. Sitting leaning forward from the waist, arms resting on pillows on a table, feet on the floor
5. Standing relaxed, leaning forwards with arms resting on a support such as a window sill.
6. Standing relaxed, leaning back against a wall with legs slightly apart.
7. Standing relaxed leaning sideways against a wall, arms in pockets if support is needed for the accessory muscles.
8. Occasionally, lying flat is beneficial because of pressure from the abdominal contents against the diaphragm. A few patients even find a slight head-down tip helpful. "

Outcome Measures

• Dyspnoea is a symptom, not an illness. 
• The outcomes are highly variable depending on the exact aetiology and patient demographics
• Dyspnea Management Questionnaire (DMQ),
• Borg Rating Of Perceived Exertion