Interstitial Cystitis: Difference between revisions
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== Diagnostic Tests/Lab Tests/Lab Values == | == Diagnostic Tests/Lab Tests/Lab Values == | ||
Diagnostic approaches for IC vary widely and there is not a general agreement on a diagnostic algorithm. Currently, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Criteria is used.<br> | Diagnostic approaches for IC vary widely and there is not a general agreement on a diagnostic algorithm. Currently, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Criteria is used.<br> | ||
NIDDK Diagonostic Critera for Interstitial Cystitis (MacDiarmid SA) | NIDDK Diagonostic Critera for Interstitial Cystitis (MacDiarmid SA) | ||
Automatic Inclusion: | Automatic Inclusion: | ||
*Hunner's ulcer | *Hunner's ulcer | ||
<br>Positive factors (2 must be present for inclusion): | <br>Positive factors (2 must be present for inclusion): | ||
*Pain on bladder filling relieved by emptying | *Pain on bladder filling relieved by emptying | ||
*Pain (suprapublic, pelvic, urethral, vaginal, or perineal) | *Pain (suprapublic, pelvic, urethral, vaginal, or perineal) | ||
*Glomerulations on cystoscopy | *Glomerulations on cystoscopy | ||
*Decreased compliance on cystometrogram | *Decreased compliance on cystometrogram | ||
<br>Exclsuions: | <br>Exclsuions: | ||
*Nocturia < 2 times per night | *Nocturia < 2 times per night | ||
*Symptoms duration < 12 months | *Symptoms duration < 12 months | ||
*Bladder Capacity > 400 mL | *Bladder Capacity > 400 mL | ||
*Involuntary bladder contractions | *Involuntary bladder contractions | ||
*Other causes of sxs: | *Other causes of sxs: | ||
Bladder Cancer, Cystitis (radiation, tuberculous, bacterial, vaginitis, active herpes, bladder or lower calculi, involuntary bladder contractions. | Bladder Cancer, Cystitis (radiation, tuberculous, bacterial, vaginitis, active herpes, bladder or lower calculi, involuntary bladder contractions. | ||
Three consensus panels concluded that the diagnosis is suspected on the basis of history, physical examination, and laboratory tests, including negative urinalysis, negative urine culture, negative cytology, and possibly cystoscopy findings. (Nickel JC) | |||
<br> | <br> | ||
Revision as of 02:45, 18 February 2010
Original Editors - Students from Bellarmine University's Pathophysiology of Complex Patient Problems project.
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Definition/Description[edit | edit source]
Interstitial cystitis (IC) aka. Painful Bladder Syndrome (PBS) is a disorder affecting the bladder characterized by uroepithelial inflammation and/or hypersenstivity of the afferent nerves of the bladder.(Oyama, IA) The International Continence Society definition is "the complaint of suprapubic pain related to bladder filling, accompanied by other symptoms such as increased daytime and night time frequency, in the absence of proven urinary infection or other obvious pathology." (Bharucha & Trabuco)
Prevalence[edit | edit source]
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Characteristics/Clinical Presentation[edit | edit source]
Associated Co-morbidities[edit | edit source]
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Medications[edit | edit source]
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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]
Diagnostic approaches for IC vary widely and there is not a general agreement on a diagnostic algorithm. Currently, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Criteria is used.
NIDDK Diagonostic Critera for Interstitial Cystitis (MacDiarmid SA)
Automatic Inclusion:
- Hunner's ulcer
Positive factors (2 must be present for inclusion):
- Pain on bladder filling relieved by emptying
- Pain (suprapublic, pelvic, urethral, vaginal, or perineal)
- Glomerulations on cystoscopy
- Decreased compliance on cystometrogram
Exclsuions:
- Nocturia < 2 times per night
- Symptoms duration < 12 months
- Bladder Capacity > 400 mL
- Involuntary bladder contractions
- Other causes of sxs:
Bladder Cancer, Cystitis (radiation, tuberculous, bacterial, vaginitis, active herpes, bladder or lower calculi, involuntary bladder contractions.
Three consensus panels concluded that the diagnosis is suspected on the basis of history, physical examination, and laboratory tests, including negative urinalysis, negative urine culture, negative cytology, and possibly cystoscopy findings. (Nickel JC)
Causes[edit | edit source]
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Systemic Involvement[edit | edit source]
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Medical Management (current best evidence)[edit | edit source]
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Physical Therapy Management (current best evidence)[edit | edit source]
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Alternative/Holistic Management (current best evidence)[edit | edit source]
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Differential Diagnosis[edit | edit source]
Case Reports[edit | edit source]
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Resources
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Recent Related Research (from Pubmed)[edit | edit source]
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References[edit | edit source]
Mac Diarmid SA, Sand PK. Diagnosis of Interstitial Cystitis/Painful Bladder Syndrome in Patients with Overactive Bladder Symptoms. Rev. Urol. 2007; 9 (1): 9-16.
Oyama IA, Reijba A, Lukban JC, Fletcher E, et al. Modified Thiele Massage as Therapeutic Intervention for female Patients with Interstitial Cystitis and High-Tone Pelvic Floor Dysfunction. Urology.; 64 (5): 862-865.
