Ovarian Cancer: Difference between revisions

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== Definition/Description  ==
== Definition/Description  ==


The term "ovarian cancer" encompasses several types of cancer that all arise from cells of the ovaries in the female reproductive system.<ref name="Green">Green A. Ovarian Cancer (Cancer of the Ovaries). MedicineNet.com. http://www.medicinenet.com/ovarian_cancer/article.htm. Updated September 24, 2013. Accessed March 12, 2014.</ref>&nbsp;Ovarian cancer commonly manifests as three different types including epithelial (cells on the surface of the ovary), fallopian tube, and primary periotoneal (lining inside the abdomen). Epithelial ovarian cancer accounts for about 70% of all ovarian cancers, making it the most common type.<ref name="Green" />&nbsp;The four most common cell types of epithelial ovarian cancer are serous, mucinous, clear cell, and endometrioid. Of these cell types, serous is the most common variety.<ref name="Green" />&nbsp;Ovarian cancer is believed to occur due to changes in cell DNA. Unfortunately, ovarian cancer often goes undiagnosed until advanced stages of the disease when it is hardest to identify the initial source.<br>
The term "ovarian cancer" encompasses several types of cancer that all arise from cells of the ovaries in the female reproductive system.<ref name="Green">Green A. Ovarian Cancer (Cancer of the Ovaries). MedicineNet.com. http://www.medicinenet.com/ovarian_cancer/article.htm. Updated September 24, 2013. Accessed March 12, 2014.</ref>&nbsp;Ovarian cancer commonly manifests as three different types including epithelial (cells on the surface of the ovary), fallopian tube, and primary periotoneal (lining inside the abdomen). Epithelial ovarian cancer accounts for about 70% of all ovarian cancers, making it the most common type.<ref name="Green" />&nbsp;The four most common cell types of epithelial ovarian cancer are serous, mucinous, clear cell, and endometrioid. Of these cell types, serous is the most common variety.<ref name="Green" />&nbsp;Ovarian cancer is believed to occur due to changes in cell DNA. Unfortunately, ovarian cancer often goes undiagnosed until advanced stages of the disease when it is hardest to identify the initial source.<br>  


== Prevalence and Incidence&nbsp;<br>  ==
== Prevalence and Incidence&nbsp;<br>  ==
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== Characteristics/Clinical Presentation  ==
== Characteristics/Clinical Presentation  ==


Epithelial ovarian cancer presents with a wide variety of vague and nonspecific symptoms.<ref name="Medscape">Green A. Ovarian Cancer. Medscape. http://emedicine.medscape.com/article/255771-overview#a0101. Published 1994-2014. Updated March 10, 2014. Accessed March 12, 2014.</ref> including bloating, abdominal distension or discomfort, pressure effects on the bladder and rectum, constipation, vaginal bleeding, indigestion and acid reflux, shortness of breath, tiredness, weight loss, and early satiety. The patient may feel an abdominal mass. Physical findings are uncommon in patients with early disease. Patients with more advanced disease may present with ovarian or pelvic mass, ascites, pleural effusion, or abdominal mass or bowel obstruction.
Epithelial ovarian cancer presents with a wide variety of vague and nonspecific symptoms.<ref name="Medscape">Green A. Ovarian Cancer. Medscape. http://emedicine.medscape.com/article/255771-overview#a0101. Published 1994-2014. Updated March 10, 2014. Accessed March 12, 2014.</ref>&nbsp;Ovarian cancer may cause one or more of these signs and symptoms--  
 
<br>
 
Ovarian cancer may cause one or more of these signs and symptoms--  


*&nbsp; &nbsp; &nbsp;Bloating, which is when the area below your stomach swells or feels full&nbsp;<ref name="Medscape" /><ref name="CDC" />  
*&nbsp; &nbsp; &nbsp;Bloating, which is when the area below your stomach swells or feels full&nbsp;<ref name="Medscape" /><ref name="CDC" />  
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*&nbsp; &nbsp; &nbsp;Back pain&nbsp;<ref name="CDC" />  
*&nbsp; &nbsp; &nbsp;Back pain&nbsp;<ref name="CDC" />  
*&nbsp; &nbsp; &nbsp;Feeling full quickly while eating&nbsp;<ref name="CDC" /><ref name="Medscape" />  
*&nbsp; &nbsp; &nbsp;Feeling full quickly while eating&nbsp;<ref name="CDC" /><ref name="Medscape" />  
*&nbsp; &nbsp; &nbsp;Painful urinination or frequent urges, constipation, or diarrhea&nbsp;<ref name="CDC">Ovarian Cancer. Center for Disease Control and Prevention. http://www.cdc.gov/cancer/ovarian/index.htm. Updated June 17, 2013. Accessed March 12, 2014.&amp;amp;amp;lt;/ref&amp;amp;amp;gt;</ref>  
*&nbsp; &nbsp; &nbsp;Painful urinination or frequent urges, constipation, or diarrhea&nbsp;<ref name="CDC">Ovarian Cancer. Center for Disease Control and Prevention. http://www.cdc.gov/cancer/ovarian/index.htm. Updated June 17, 2013. Accessed March 12, 2014.&amp;amp;amp;amp;lt;/ref&amp;amp;amp;amp;gt;</ref>  
*&nbsp; &nbsp; &nbsp;Indigestion and acid reflux&nbsp;  
*&nbsp; &nbsp; &nbsp;Indigestion and acid reflux&nbsp;<ref name="Medscape" />
*&nbsp; &nbsp; &nbsp;Shortness of breath (SOB)  
*&nbsp; &nbsp; &nbsp;Shortness of breath (SOB)&nbsp;<ref name="Medscape" />
*&nbsp; &nbsp; &nbsp;Weight Loss  
*&nbsp; &nbsp; &nbsp;Weight Loss<br>
*
 
Physical findings are uncommon in patients with early disease, but the more advanced the disease one may present with ovarian or pelvic mass, ascites, pleural effusion, or abdominal mass or bowel obstruction.&nbsp;<ref name="Medscape" />&nbsp;Pay attention to your body, and know what is normal for you. If you have vaginal bleedingand/or an abnormal menstral cycle that is not normal for you, see a physician right away. The key is early intervention so the earlier ovarian cancer is found and treated, the more likely treatment will be effective. <ref name="CDC" />


&nbsp; &nbsp; &nbsp;  
&nbsp; &nbsp; &nbsp;  

Revision as of 01:03, 25 March 2014

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Definition/Description[edit | edit source]

The term "ovarian cancer" encompasses several types of cancer that all arise from cells of the ovaries in the female reproductive system.[1] Ovarian cancer commonly manifests as three different types including epithelial (cells on the surface of the ovary), fallopian tube, and primary periotoneal (lining inside the abdomen). Epithelial ovarian cancer accounts for about 70% of all ovarian cancers, making it the most common type.[1] The four most common cell types of epithelial ovarian cancer are serous, mucinous, clear cell, and endometrioid. Of these cell types, serous is the most common variety.[1] Ovarian cancer is believed to occur due to changes in cell DNA. Unfortunately, ovarian cancer often goes undiagnosed until advanced stages of the disease when it is hardest to identify the initial source.

Prevalence and Incidence 
[edit | edit source]

     Over 22,000 new cases of ovarian cancer are diagnosed each year. There will be about 15,000 deaths annually from this condition. [2] 

Characteristics/Clinical Presentation[edit | edit source]

Epithelial ovarian cancer presents with a wide variety of vague and nonspecific symptoms.[3] Ovarian cancer may cause one or more of these signs and symptoms--

  •      Bloating, which is when the area below your stomach swells or feels full [3][4]
  •      Vaginal bleeding or discharge (not normal for individual) [4][3]
  •      Pain in the pelvic or abdominal area, abdominal distension or discomfort, abdominal mass [4][3]
  •      Back pain [4]
  •      Feeling full quickly while eating [4][3]
  •      Painful urinination or frequent urges, constipation, or diarrhea [4]
  •      Indigestion and acid reflux [3]
  •      Shortness of breath (SOB) [3]
  •      Weight Loss

Physical findings are uncommon in patients with early disease, but the more advanced the disease one may present with ovarian or pelvic mass, ascites, pleural effusion, or abdominal mass or bowel obstruction. [3] Pay attention to your body, and know what is normal for you. If you have vaginal bleedingand/or an abnormal menstral cycle that is not normal for you, see a physician right away. The key is early intervention so the earlier ovarian cancer is found and treated, the more likely treatment will be effective. [4]

     

Associated Co-morbidities[edit | edit source]

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Medications[edit | edit source]

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Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Etiology/Causes[edit | edit source]

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Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Alternative/Holistic Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports/ Case Studies[edit | edit source]

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Resources
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Recent Related Research (from Pubmed)[edit | edit source]

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References[edit | edit source]

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  1. 1.0 1.1 1.2 Green A. Ovarian Cancer (Cancer of the Ovaries). MedicineNet.com. http://www.medicinenet.com/ovarian_cancer/article.htm. Updated September 24, 2013. Accessed March 12, 2014.
  2. Medical Information. National Ovarian Cancer Coalition. http://ovarian.org/what_is_ovarian_cancer.php. Accessed March 12, 2014.
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Green A. Ovarian Cancer. Medscape. http://emedicine.medscape.com/article/255771-overview#a0101. Published 1994-2014. Updated March 10, 2014. Accessed March 12, 2014.
  4. 4.0 4.1 4.2 4.3 4.4 4.5 4.6 Ovarian Cancer. Center for Disease Control and Prevention. http://www.cdc.gov/cancer/ovarian/index.htm. Updated June 17, 2013. Accessed March 12, 2014.&amp;amp;amp;lt;/ref&amp;amp;amp;gt;