Vitamin B12 Deficiency: Difference between revisions

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== Medications  ==
== Medications  ==


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There are several different medications that can affect the absorption of vitamin B12.&nbsp; There is not sufficient or there is conflicting evidence that suggests these medcations might affect the asorption of Vitamin B12.&nbsp; Patients that use these medications should keep tract of their Vitamin B12 levels.&nbsp; Medications that can interfere with the absorption of Vitamin B12 include:
 
<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <br>-Chloramphenicol (antibiotic) May interfere with the RBC response to Vit. B12<br>-Proton Pump Inhibitors (Prilosec) These medications slow down the absorption of Vit. B12.&nbsp; They do this because they slowly release acid into the stomach. <br> <br>-H2 Receptor Antagonist (Pepcid, Zantac) These medications slow down the absorbtion of Vit. B12 by releasing hydrochloric acid into the stomach.<br>-Metformin (Hypoglycemic used for diabetes) May alter the mobility and bacteria in the intestines, or may alter the intrinsic factor needed to absorb Vit. B12.<ref name="NIH">Vitamin B12 [Internet]. [Place Unknown]: National Institutes of Health: Office of Dietary Suppliments;2009 [cited 2014 March 23]. Available at http://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/#h5.</ref> <br>


== Diagnostic Tests/Lab Tests/Lab Values  ==
== Diagnostic Tests/Lab Tests/Lab Values  ==

Revision as of 13:41, 25 March 2014

Welcome to PT 635 Pathophysiology of Complex Patient Problems This is a wiki created by and for the students in the School of Physical Therapy at Bellarmine University in Louisville KY. Please do not edit unless you are involved in this project, but please come back in the near future to check out new information!!

Definition/Description[edit | edit source]

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Prevalence[edit | edit source]

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Characteristics/Clinical Presentation[edit | edit source]

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Associated Co-morbidities[edit | edit source]

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Medications[edit | edit source]

There are several different medications that can affect the absorption of vitamin B12.  There is not sufficient or there is conflicting evidence that suggests these medcations might affect the asorption of Vitamin B12.  Patients that use these medications should keep tract of their Vitamin B12 levels.  Medications that can interfere with the absorption of Vitamin B12 include:


         
-Chloramphenicol (antibiotic) May interfere with the RBC response to Vit. B12
-Proton Pump Inhibitors (Prilosec) These medications slow down the absorption of Vit. B12.  They do this because they slowly release acid into the stomach.

-H2 Receptor Antagonist (Pepcid, Zantac) These medications slow down the absorbtion of Vit. B12 by releasing hydrochloric acid into the stomach.
-Metformin (Hypoglycemic used for diabetes) May alter the mobility and bacteria in the intestines, or may alter the intrinsic factor needed to absorb Vit. B12.[1]

Diagnostic Tests/Lab Tests/Lab Values[edit | edit source]

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Etiology/Causes[edit | edit source]

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Systemic Involvement[edit | edit source]

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Medical Management (current best evidence)[edit | edit source]

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Physical Therapy Management (current best evidence)[edit | edit source]

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Alternative/Holistic Management (current best evidence)[edit | edit source]

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Differential Diagnosis[edit | edit source]

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Case Reports/ Case Studies[edit | edit source]

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Resources
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References[edit | edit source]

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  1. Vitamin B12 [Internet]. [Place Unknown]: National Institutes of Health: Office of Dietary Suppliments;2009 [cited 2014 March 23]. Available at http://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/#h5.