Bone: Difference between revisions
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==== Gross anatomy ==== | ==== Gross anatomy ==== | ||
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==== Individual bone structure ==== | ==== Individual bone structure ==== | ||
Revision as of 18:53, 15 November 2018
This article is currently under review and may not be up to date. Please come back soon to see the finished work! (15/11/2018)
Original Editors -
Top Contributors - Lucinda hampton, Candace Goh, Admin, Shaimaa Eldib, Kim Jackson, Wataru Okuyama, Jess Bell, Robin Tacchetti, George Prudden, Claire Knott, Manisha Shrestha, Khloud Shreif, Tony Lowe, Stephanie Geeurickx, WikiSysop, Joao Costa and Sai Kripa
Bones are connected to each other to form skeleton, which forms the framework of the body.
Functions[edit | edit source]
Mechanical[edit | edit source]
- Protect internal organs
- Give shape and support to the body
- Movement
Synthetic[edit | edit source]
- Manufactures blood cells from the bone marrow (hematopoiesis)
Metabolic[edit | edit source]
- Mineral storage
- Fat storage
- Role in acid-base balance
Structure[edit | edit source]
Gross anatomy[edit | edit source]
Individual bone structure[edit | edit source]
- Compact/cortical bone
- Cancellous/spongy bone
Cellular structure[edit | edit source]
Osteoblasts
Osteoclasts
Osteocytes
Molecular structure[edit | edit source]
Matrix[edit | edit source]
- Inorganic
- Organic
Woven or lamellar[edit | edit source]
Types[edit | edit source]
Formation[edit | edit source]
Intramembranous ossification[edit | edit source]
Endochondral ossification[edit | edit source]
Bone marrow[edit | edit source]
Remodeling[edit | edit source]
Purpose[edit | edit source]
Calcium homeostasis/balance must exist between osteoclasts and osteoblasts activity[edit | edit source]
- If too much new tissue is formed, the bones become abnormally large and thick (acromegaly)
- Excessive loss of calcium weakens the bones, as occurs in osteoporosis
Repair[edit | edit source]
Paracrine cell signalling[edit | edit source]
Osteoblast stimulation[edit | edit source]
Osteoclast inhibition[edit | edit source]
Disorders[edit | edit source]
- Osteoporosis
- Osteoarthritis
- Osteomalacia
- Rickets
- Epiphyseal plate disorders
References[edit | edit source]
see adding references tutorial.
