Bone
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Original Editors -
Top Contributors - Lucinda hampton, Candace Goh, Admin, Shaimaa Eldib, Kim Jackson, Wataru Okuyama, Jess Bell, Robin Tacchetti, George Prudden, Claire Knott, Manisha Shrestha, Khloud Shreif, Sai Kripa, Tony Lowe, Stephanie Geeurickx, WikiSysop and Joao Costa
Bones are connected to each other to form skeleton, which forms the framework of the body.
Functions[edit | edit source]
Mechanical[edit | edit source]
- Protection
- Shape
- Movement
Synthetic[edit | edit source]
- Synthesis of blood cells
Metabolic[edit | edit source]
- Mineral storage
- Fat storage
- Role in acid-base balance
Position patella[edit | edit source]
Structure[edit | edit source]
Gross anatomy[edit | edit source]
Individual bone structure[edit | edit source]
- Compact (cortical) bone
- Trabecular bone
Cellular structure[edit | edit source]
Molecular structure[edit | edit source]
Matrix[edit | edit source]
- Inorganic
- Organic
Woven or lamellar[edit | edit source]
Types[edit | edit source]
Formation[edit | edit source]
Intramembranous ossification[edit | edit source]
Endochondral ossification[edit | edit source]
Bone marrow[edit | edit source]
Remodeling[edit | edit source]
Purpose[edit | edit source]
Calcium homeostasis/balance must exist between osteoclasts and osteoblasts activity[edit | edit source]
- If too much new tissue is formed, the bones become abnormally large and thick (acromegaly)
- Excessive loss of calcium weakens the bones, as occurs in osteoporosis
Repair[edit | edit source]
Paracrine cell signalling[edit | edit source]
Osteoblast stimulation[edit | edit source]
Osteoclast inhibition[edit | edit source]
Disorders[edit | edit source]
- Osteoporosis
- Osteoarthritis
- Osteomalacia
- Rickets
- Epiphyseal plate disorders
References[edit | edit source]
see adding references tutorial.
